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经验公式(希尔记法):
C11H18NOCl
化学文摘社编号:
分子量:
215.72
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
产品名称
CP-24879 hydrochloride, ≥98% (HPLC), powder
Quality Level
InChI key
GFESZSNFRSACMU-UHFFFAOYSA-N
SMILES string
Cl[H].CC(C)CCOc1ccc(N)cc1
InChI
1S/C11H17NO.ClH/c1-9(2)7-8-13-11-5-3-10(12)4-6-11;/h3-6,9H,7-8,12H2,1-2H3;1H
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to brown
mp
154-159 °C
solubility
DMSO: 10 mg/mL, clear
storage temp.
room temp
Biochem/physiol Actions
delta5/delta6 (Δ5/Δ6) desaturase inhibitor.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
Ji-Yoon Lee et al.
Proceedings of the National Academy of Sciences of the United States of America, 117(51), 32433-32442 (2020-12-09)
Ferroptosis is an iron-dependent regulated necrosis mediated by lipid peroxidation. Cancer cells survive under metabolic stress conditions by altering lipid metabolism, which may alter their sensitivity to ferroptosis. However, the association between lipid metabolism and ferroptosis is not completely understood.
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