所有图片(4)

文件

C9377

鹅去氧胆酸

Name: 鹅去氧胆酸
Brand: SIGMA

登录查看公司和协议定价

所有图片(4)

别名:

3α，7α-二羟基-5β-胆汁酸, 5β-胆酸-3α，7α-二醇, 鹅去氧胆酸

经验公式（希尔记法）:

C₂₄H₄₀O₄

CAS号:

474-25-9

分子量:

392.57

Beilstein:

3219887

EC 号:

207-481-8

MDL编号:

MFCD00064142

PubChem化学物质编号:

24893153

NACRES:

NA.25

描述

anionic

质量水平

200

形式

powder

分子量

392.57 g/mol

technique(s)

protein quantification: suitable

CMC

(3)
3

mp

165-167 °C (lit.)

官能团

carboxylic acid

运输

ambient

储存温度

room temp

SMILES string

C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

InChI

1S/C24H40O4/c1-14(4-7-21(27)28)17-5-6-18-22-19(9-11-24(17,18)3)23(2)10-8-16(25)12-15(23)13-20(22)26/h14-20,22,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15+,16-,17-,18+,19+,20-,22+,23+,24-/m1/s1

InChI key

RUDATBOHQWOJDD-BSWAIDMHSA-N

Gene Information

human ... CYP1A2(1544) , NR1H4(9971)

正在寻找类似产品? Visit 产品对比指南

一般描述

鹅去氧胆酸是胆固醇在肝脏中合成的胆汁酸。

应用

鹅去氧胆酸已被用于一项评估其作为脑腱黄色瘤病（CTX）的长期替代疗法的效果的研究中。它也被用于一项研究其对回肠造口患者小肠吸收胆汁酸的影响的研究中。

生化/生理作用

胆汁酸

象形图

GHS07

警示用语：

Warning

危险声明

H315 - H319

预防措施声明

P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313

危险分类

Eye Irrit. 2 - Skin Irrit. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

分析证书(COA)

输入产品批号来搜索分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

为方便起见，与您过往购买产品相关的文件已保存在文档库中。

访问文档库

难以找到您所需的产品或批次号码？

如何查找产品货号

在网站页面上，产品编号会附带包装尺寸/数量一起显示（例如：T1503-25G）。请确保在“产品编号”字段中仅输入产品编号 (示例: T1503).

示例

T1503

货号

25G

包装规格/数量

其它示例：

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

输入内容 1.000309185)

遇到问题？欢迎随时联系我们技术服务寻求帮助

如何查找COA批号

批号可以在产品标签上"批“ （Lot或Batch）字后面找到。

Aldrich 产品

如果您查询到的批号为 TO09019TO 等，请输入去除前两位字母的批号：09019TO。
如果您查询到的批号含有填充代码（例如05427ES-021），请输入去除填充代码-021的批号：05427ES。
如果您查询到的批号含有填充代码（例如 STBB0728K9），请输入去除填充代码K9的批号：STBB0728。

未找到您寻找的产品？

部分情况下，可能未在线提供COA。如果搜索不到COA，可在线索取。

索取COA

A monoclonal anti-interleukin 8 antibody (WS-4) inhibits cytokine response and acute lung injury in experimental severe acute necrotising pancreatitis in rabbits.

M O Osman et al.

Gut, 43(2), 232-239 (1999-04-06)

Interleukin 8 (IL-8) has recently been proposed to have an important role in mediating the development of the systemic sequelae associated with severe acute pancreatitis. To define the role of IL-8 in acute pancreatitis by neutralising its effects with a

Gallstone dissolution in man using chenodeoxycholic acid

Bell, G., et al.

Lancet, 300, 1213-1213 null

Acute effects of ursodeoxycholic and chenodeoxycholic acid on the small intestinal absorption of bile acids.

A Stiehl et al.

Gastroenterology, 98(2), 424-428 (1990-02-01)

The effects of ursodeoxycholic acid and chenodeoxycholic acid on the small-intestinal absorption of endogenous bile acids were studied in patients with ileostomies who served as a model to investigate small-intestinal absorption in humans. In the control period, the eight patients

Development and validation of a high-throughput screening assay for human long-chain fatty acid transport proteins 4 and 5.

Wei Zhou et al.

Journal of biomolecular screening, 15(5), 488-497 (2010-05-08)

Dietary long-chain fatty acid (LCFA) uptake across cell membranes is mediated principally by fatty acid transport proteins (FATPs). Six subtypes of this transporter are differentially expressed throughout the human and rodent body. To facilitate drugs discovery against FATP subtypes, the

Isolation and characterization of hydrophobic polypeptides in human bile.

M Stark et al.

European journal of biochemistry, 266(1), 209-214 (1999-10-29)

Polypeptides were isolated from human bile by extraction with chloroform/methanol, followed by reversed-phase chromatography in methanol/ethylene chloride and gel filtration in chloroform/methanol. Peptides were characterized by SDS/PAGE, sequence analysis and matrix-assisted laser desorption ionization/time-of-flight mass spectrometry. This identified haemoglobin alpha

查看所有相关文献

实验方案

Fast and Robust HPLC Separation of Bile Acids and Conjugates with Ascentis Express C18

This method is particularly useful in research into the role of individual bile acids as signaling molecules; suitable for clinical laboratories to investigate potential mechanisms linked to gut hormone profiles and glycemic control.

文件