C9500
(±)-肉碱 盐酸盐
≥98% (TLC)
别名:
β-Hydroxy-γ-(trimethylammonio)butyrate 盐酸盐, (±)-Carnitine chloride, 盐酸盐
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关于此项目
线性分子式:
(CH3)3N(Cl)CH2CH(OH)CH2COOH
化学文摘社编号:
分子量:
197.66
NACRES:
NA.26
PubChem Substance ID:
UNSPSC Code:
12352107
EC Number:
207-309-1
MDL number:
Beilstein/REAXYS Number:
4163212
产品名称
(±)-肉碱 盐酸盐, ≥98% (TLC)
InChI key
JXXCENBLGFBQJM-UHFFFAOYSA-N
InChI
1S/C7H15NO3.ClH/c1-8(2,3)5-6(9)4-7(10)11;/h6,9H,4-5H2,1-3H3;1H
SMILES string
[Cl-].C[N+](C)(C)CC(O)CC(O)=O
assay
≥98% (TLC)
form
powder
color
white
Quality Level
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Application
DL-肉毒碱是具有活性的季铵盐立体异构体、 L-肉毒碱和无生物活性的 D-肉毒碱的外消旋混合物。DL-肉毒碱用于与纯异构体的比较研究。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
A A Spasov et al.
Bulletin of experimental biology and medicine, 142(4), 458-460 (2007-04-07)
Serum concentration of L-carnitine, the mean thickness of the skeletal muscle fiber, and exercise performance in the forced swimming test decreased in rats receiving a carnitine-deficient diet. Treatment with L-carnitine compensated for carnitine deficiency, while racemate and D-stereoisomer did not
A A Spasov et al.
Vestnik Rossiiskoi akademii meditsinskikh nauk, 7(7), 20-27 (2006-08-24)
L-carnitine (L-beta-hydroxy-gamma-N,N,N-trimethylaminobutyric acid) is conditionally necessary for mitochondrial transport and metabolism of long-chain fatty acids, and thus for myocardial energetic metabolism. D-carnitine is not biologically active and might interfere with proper utilization of the L isomer, and so there are
A A Spasov et al.
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova, 91(12), 1469-1480 (2006-02-24)
L-Carnitine (L-beta-hydroxy-gamma-N,N,N-trimethylaminobutyric acid) plays an essential role in fatty acid transport in the mitochondrion. Conditions that appear to benefit from exogenous supplementation of L-carnitine include anorexia, chronic fatigue, cardiovascular disease, hypoglycemia, male infertility, muscular myopathies, renal failure and dialysis. D-Carnitine
Sophie Schobesberger et al.
eLife, 9 (2020-04-02)
Cardiomyocyte β3-adrenoceptors (β3-ARs) coupled to soluble guanylyl cyclase (sGC)-dependent production of the second messenger 3',5'-cyclic guanosine monophosphate (cGMP) have been shown to protect from heart failure. However, the exact localization of these receptors to fine membrane structures and subcellular compartmentation
Dinesh D Jayasena et al.
Journal of the science of food and agriculture, 95(4), 771-775 (2014-08-27)
In this study the effects of sex, meat cut and thermal processing on the carnosine, anserine, creatine, betaine and carnitine contents of Korean native chicken (KNC) meat were determined. Forty 1-day-old chicks (20 chicks of each sex) from a commercial
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