C9650
β-氰基- L -丙氨酸
≥95%, suitable for ligand binding assays
别名:
3-cyano-L-alanine
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关于此项目
经验公式（希尔记法）:
C4H6N2O2
化学文摘社编号:
分子量:
114.10
UNSPSC Code:
12352209
PubChem Substance ID:
NACRES:
NA.26
MDL number:
产品名称
β-氰基- L -丙氨酸, ≥95%
SMILES string
OC([C@@H](N)CC#N)=O
InChI
1S/C4H6N2O2/c5-2-1-3(6)4(7)8/h3H,1,6H2,(H,7,8)/t3-/m0/s1
InChI key
BXRLWGXPSRYJDZ-VKHMYHEASA-N
assay
≥95%
form
powder
technique(s)
ligand binding assay: suitable
color
white
mp
217 °C
storage temp.
−20°C
Quality Level
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Biochem/physiol Actions
β-氰基-L-丙氨酸 (BCA) 用作胱硫醚 γ-裂解酶 (CSE) 抑制剂，研究硫化氢在血管新生和高血压等过程中的生理作用。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
B Teague et al.
British journal of pharmacology, 137(2), 139-145 (2002-09-05)
1. Sodium hydrogen sulphide (NaHS), a donor of hydrogen sulphide (H(2)S), produced dose-related relaxation of the rabbit isolated ileum (EC(50), 76.4+/-7.9 microM) and rat vas deferens (EC(50), 64.8+/-5.4 microM) and reduced ACh-mediated contraction of the guinea-pig isolated ileum. 2. NaHS
Andrew J M Howden et al.
The Plant journal : for cell and molecular biology, 57(2), 243-253 (2008-09-13)
Pseudomonas fluorescens SBW25 is a plant growth-promoting bacterium that efficiently colonizes the leaf surfaces and rhizosphere of a range of plants. Previous studies have identified a putative plant-induced nitrilase gene (pinA) in P. fluorescens SBW25 that is expressed in the
Markus Piotrowski et al.
Plant molecular biology, 61(1-2), 111-122 (2006-06-21)
Cyanoalanine hydratase (E.C. 4.2.1.65) is an enzyme involved in the cyanide detoxification pathway of higher plants and catalyzes the hydrolysis of beta-cyano-L-alanine to asparagine. We have isolated the enzyme from seedlings of blue lupine (Lupinus angustifolius) to obtain protein sequence
Andrew G S Warrilow et al.
Journal of experimental botany, 53(368), 439-445 (2002-02-16)
The reaction mechanisms of three enzymes belonging to a single gene family are compared: a cyanoalanine synthase and two isoforms of O-acetylserine (thiol) lyase (O-ASTL) isolated from spinach (Spinacea oleracea L. cv. Medina). O-ASTL represents a major regulatory point in
Liping Fang et al.
Journal of hypertension, 27(11), 2174-2185 (2009-08-01)
Recently, periadventitial adipose tissue (PAT) was found to secrete bioactive factors playing an important role in the regulation of vascular tension. Hydrogen sulfide (H(2)S), a novel cardiovascular gasotransmitter, relaxes vessels through the K(ATP) channel in a calcium-dependent and endothelial-independent manner.
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