CAMKIγ (CLICK-III), a member of CAMK family, is a novel membrane-anchored neuronal Ca²⁺/calmodulin-dependent protein kinase. Full activation of CaMKIγ requires both Ca²⁺/CaM and phosphorylation by CAMKK. CAMKIγ transcripts is most abundant in neurons, with the highest levels in limited nuclei such as the central nucleus of the amygdala (CeA) and the ventromedial hypothalamus.

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