C9749
CBiPES hydrochloride
≥98% (HPLC)
别名:
N-(4′-cyano[1,1′-biphenyl]-3-yl)-N-(3-pyridinylmethyl)-ethanesulfonamide hydrochloride
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关于此项目
经验公式（希尔记法）:
C21H19N3O2S · HCl
化学文摘社编号:
分子量:
413.92
MDL编号:
UNSPSC代码:
12352200
NACRES:
NA.77
质量水平
方案
≥98% (HPLC)
表单
powder
储存条件
desiccated
颜色
off-white to light brown
溶解性
DMSO: >20 mg/mL
创始人
Eli Lilly
储存温度
2-8°C
SMILES字符串
[S](=O)(=O)(N(Cc3cnccc3)c1cc(ccc1)c2ccc(cc2)C#N)CC.Cl
InChI
1S/C21H19N3O2S.ClH/c1-2-27(25,26)24(16-18-5-4-12-23-15-18)21-7-3-6-20(13-21)19-10-8-17(14-22)9-11-19;/h3-13,15H,2,16H2,1H3;1H
InChI key
QKUHSVQWWZBAKM-UHFFFAOYSA-N
生化/生理作用
CBiPES is a positive allosteric modulator of the mGlu2 receptor.
CBiPES is a positive allosteric modulator of the mGlu2 receptor. CBiPES attenuates stress-induced hyperthermia and blocks the hyperlocomotor effects of PCP in murine models. In rat brain, CBiPES attenuates ketamine-induced increase in extracellular histamine concentration. This compound is a sulfonamide, different chemical class from other mGlu2R agonists in the Sigma catalog.
特点和优势
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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