COR-L105

COR-L105 cell line has been used to identify chromosomal aberrations by using multicolor fluorescent in situ hybridization (M-FISH) and comparative genomic hybridization (CGH).

Derived from the pleural effusion of a Caucasian male. Cells grow partially attached and in suspension.

Human Caucasian lung adenocarcinoma

STR-PCR Data: Amelogenin: X,Y
CSF1PO: 9,11
D13S317: 10,11
D16S539: 11,12
D5S818: 11,12
D7S820: 8,11
THO1: 8,9.3
TPOX: 8,11
vWA: 16,17

RPMI 1640 + 2mM Glutamine + 10% Foetal Bovine Serum (FBS).

Split sub-confluent cultures (70-80%) 1:3 to 1:6 i.e. seeding at 3-6x10,000 cells/cm² using 0.25% trypsin/EDTA; 5% CO₂; 37°C. Cells grow in colonies and do not form a confluent monolayer.

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This cell line is part of the European Collection of Authenticated Cell Cultures (ECACC), an international repository managed by the United Kingdom Health Security Agency (UKHSA). No licensing agreement is required when either this cell line or the DNA extracted from it are used for internal research purposes only. Any other use of these products is prohibited without the express written permission of UKHSA. Inquiries regarding authorized use of this cell line or its genomic DNA may be directed to culturecollections@ukhsa.gov.uk.