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C6 Cell Line from rat

NOTE: Both the cell line and DNA from the cell line may be available for this product. Please choose -1VL or VIAL for cells, or -DNA-5UG for DNA, 92090409, rat nerve (glial tumor), Neuronal

别名:

C-6 Cells, RGC-6 Cells

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关于此项目

UNSPSC Code:
41106514
Biological source:
rat nerve (glial tumor)
Relevant disease(s):
cancer
Growth mode:
Adherent
Karyotype:
2n = 42
Morphology:
Neuronal
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biological source

rat nerve (glial tumor)

description

Rat glial tumor

packaging

tube of 5 μg 92090409-DNA-5UG, pkg of vial of cells 92090409-1VL

growth mode

Adherent

karyotype

2n = 42

morphology

Neuronal

products

S-100 protein, somatotrophin

receptors

Not specified

technique(s)

cell culture | mammalian: suitable

relevant disease(s)

cancer

shipped in

dry ice

storage temp.

−196°C

Application

C6 cell line has been used to study the ability of 2-(2,4-dihydroxyphenyl)thieno-1,3-thiazin-4-one (BChTT) to inhibit cancer cell proliferation and identify mechanisms involved in its actions. It has also been used to study the cytotoxic and antioxidant properties of supercritical CO2 extract (SCE) of old man′s beard (Usnea barbata).
C6 cells are reported to produce elevated levels of glyceryl phosphate dehydrogenase activity in response to glucocorticoids

Biochem/physiol Actions

Derived from a rat glial tumour induced by N-nitrosomethylurea. The cells produce S-100 protein which is found in the neural tissue of vertebrates and has been found in brain tumours. Synthesis of S-100 increases 10 fold as cells reach confluency.
Rat glial tumour

Preparation Note

Ham′s F12 + 2mM Glutamine + 10% Foetal Bovine Serum (FBS).
Split sub-confluent cultures (70-80%) 1:3 to 1:6 i.e. seeding at 1-3x100,000 cells/cm2 using 0.25% trypsin or trypsin/EDTA; 5% CO2; 37°C.

Other Notes

Additional freight & handling charges may be applicable for Asia-Pacific shipments. Please check with your local Customer Service representative for more information.

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