COR-L24

Cytotoxicity studies, study of small cell lung cancer

Human lung small cell carcinoma

STR-PCR Data: Amelogenin: X
CSF1PO: 11
D13S317: 12
D16S539: 12
D5S818: 11
D7S820: 11
THO1: 7,9.3
TPOX: 8
vWA: 16,17

The cell line COR-L24 was established from a lymph node biopsy of an untreated 71 year old male and was diagnosed as small cell lung carcinoma (SCLC). Bone marrow taken from the same patient contained hypercellular marrow consistent with normal haemopoietic cells and no evidence of neoplasm. In culture, this xenograft forming cell line grows as floating aggregates of packed cells with irregular shape.

Maintain cultures between 3-9 x 100,000 cells/ml; 5% CO₂; 37°C.

RPMI 1640 + 2mM Glutamine + 10% Foetal Bovine Serum (FBS).

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This cell line is part of the European Collection of Authenticated Cell Cultures (ECACC), an international repository managed by the United Kingdom Health Security Agency (UKHSA). No licensing agreement is required when either this cell line or the DNA extracted from it are used for internal research purposes only. Any other use of these products is prohibited without the express written permission of UKHSA. Inquiries regarding authorized use of this cell line or its genomic DNA may be directed to culturecollections@ukhsa.gov.uk.