COR-L32

Lung cancer study

Human small cell carcinoma

The cell line COR-L32 has been estalished from a marrow trephine from a poorly-differentiated squamous cell carcinoma. The patient has been confirmed to have primary lung cancer. Electron micrographs showed dense core granules and other features of neuroendocrine differentiation. In culture, COR-L32 grow as floating aggregates of packed cells.

Maintain cultures between 3-9 x 100,000 cells / ml; 5% CO₂; 37°C. This is a human small cell carcinoma which grows in large clumps. Cell banks should be frozen at high cell densities e.g. 6-9 x 1000,000 cells/ml to allow for clumping.

RPMI 1640 + 2mM Glutamine + 10% Foetal Bovine Serum (FBS).

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This cell line is part of the European Collection of Authenticated Cell Cultures (ECACC), an international repository managed by the United Kingdom Health Security Agency (UKHSA). No licensing agreement is required when either this cell line or the DNA extracted from it are used for internal research purposes only. Any other use of these products is prohibited without the express written permission of UKHSA. Inquiries regarding authorized use of this cell line or its genomic DNA may be directed to culturecollections@ukhsa.gov.uk.