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Merck
CN

CL4B200

Sepharose CL-4B Size Exclusion Resin

Cross-linked, 90-350 mesh

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化学文摘社编号:
UNSPSC Code:
23151817
NACRES:
SB.52
MDL number:
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产品名称

Sepharose CL-4B, Cross-linked

form

beads

technique(s)

LPLC: suitable

matrix

Agarose

matrix active group

polymer

bead diameter

40-165 μm

pore size

30,000-5,000,000 fractionation range (Dextrans)
60,000-20,000,000 fractionation range (Globular proteins)

separation technique

size exclusion (SEC)

storage temp.

2-8°C

Quality Level

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Application

  • 通过HPAEC-PAD和比色法进行含乳糖流感嗜血杆菌疫苗的分子尺寸分布评估:该研究将琼脂糖CL-4B用于疫苗制剂分子尺寸分布的评估方法,显示了其在疫苗生产质量控制和开发过程中的应用(Nadim AH et al., 2022)。
  • 骆驼包虫病诊断试剂盒: 采用戊二醛法优化芜菁和辣根过氧化物酶偶联物:该研究描述了琼脂糖CL-4B在诊断试剂盒开发中的用途,表明了其在通过有效的酶偶联技术改善诊断测定开发中的作用(Kandil OM et al., 2020)。
  • 来自垂枝桦叶的果胶质:NMR 实验和RG-I结构水解的结果:研究人员采用琼脂糖CL-4B来阐明来自桦树叶的果胶质的结构,该研究强调了其在多糖结构研究中的重要性,这对理解其生物学功能和工业应用是必不可少的(Golovchenko VV et al., 2022)。

General description

CL4B200-1L的更新产品编号为GE17-0150-01

Legal Information

Sepharose is a trademark of Cytiva

pictograms

Flame

signalword

Warning

hcodes

Hazard Classifications

Flam. Liq. 3

存储类别

3 - Flammable liquids

wgk

WGK 1

flash_point_f

100.4 - 109.4 °F

flash_point_c

38 - 43 °C

法规信息

危险化学品
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分析证书(COA)

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Immunoadsorbents for clinical use: ex vivo immunoglobulin E removal in allergy.
V D Gorchakov et al.
Journal of chromatography, 563(1), 166-171 (1991-01-18)
M M Diogo et al.
Journal of chromatography. A, 1006(1-2), 137-148 (2003-08-27)
The effect of salt and temperature on the interaction of homo-oligonucleotides with a derivatized Sepharose CL-6B hydrophobic support has been explained by the application of two different models: the solvophobic theory and the preferential interaction analysis. It has been shown
S Cochet et al.
Journal of chromatography. A, 663(2), 175-186 (1994-03-11)
A range of substances were screened to find eluents for human immunoglobulin G (IgG) which are retained with a strong affinity by immobilized Drimarene Rubine R/K-5BL. The strong affinity of IgG for the dye is partly due to the presence
M Zachariou et al.
Journal of chromatography, 646(1), 107-120 (1993-08-27)
Conditions for the immobilization of O-phosphoserine (OPS) to epoxy-activated Sepharose CL-4B are described. The binding behaviour of OPS and iminodiacetic acid (IDA) immobilized onto Sepharose CL-4B, toward the hard Lewis metal ions Al3+, Fe3+, Ca2+ and Yb3+, and Cu2+ ion
N Ubrich et al.
Artificial cells, blood substitutes, and immobilization biotechnology, 24(1), 65-75 (1996-01-01)
Immunoadsorption is an application of affinity chromatography, as a therapeutic method to specifically deplete biological fluids such as blood plasma from proteins in excess, or to extract a biomolecule from a complex mixture. However, the leakage of small amounts of

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