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Merck
CN

D0162

地丹诺辛

≥98% (HPLC)

别名:

ddI, ddIno

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关于此项目

经验公式(希尔记法):
C10H12N4O3
化学文摘社编号:
分子量:
236.23
UNSPSC Code:
41116107
NACRES:
NA.55
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3619529
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assay

≥98% (HPLC)

form

powder

storage temp.

−20°C

SMILES string

OC[C@@H]1CC[C@@H](O1)n2cnc3C(=O)NC=Nc23

InChI

1S/C10H12N4O3/c15-3-6-1-2-7(17-6)14-5-13-8-9(14)11-4-12-10(8)16/h4-7,15H,1-3H2,(H,11,12,16)/t6-,7+/m0/s1

InChI key

BXZVVICBKDXVGW-NKWVEPMBSA-N

Biochem/physiol Actions

核苷酸拮抗剂


存储类别

11 - Combustible Solids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

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Jan Balzarini et al.
European journal of medicinal chemistry, 44(1), 303-311 (2008-04-19)
A series of novel thiazolidin-4-ones bearing a lipophilic adamantyl substituent at position 2 or 3 were synthesized. A majority of them showed a modest anti-HIV-1 activity, whereas 2-adamantan-1-yl-3-(4,6-dimethylpyrimidin-2-yl)-thiazolidin-4-one (8) was endowed with a remarkable antiviral potency (EC(50)=0.67 microM). The new
Yuan-Zhen Xiong et al.
European journal of medicinal chemistry, 43(6), 1230-1236 (2007-09-18)
A series of novel 6-naphthyloxy substituted DATA analogues bearing different substituents on the C-6 position of triazine ring were synthesized and evaluated for their in vitro anti-HIV activity in MT-4 cells. The results demonstrated that most of the compounds in
Jan Balzarini et al.
European journal of medicinal chemistry, 42(7), 993-1003 (2007-02-27)
A series of novel thiazolidin-4-ones bearing a lipophilic adamantyl substituent at position 2, and versatile substituents on the nitrogen atom of the thiazolidine ring, were synthesized whereas several compounds exhibited a modest anti-HIV-1 activity, (+/-)-2-adamantan-1-yl-3-(4,6-dimethyl-pyridin-2-yl)-thiazolidin-4-one 22 was endowed with a



全球贸易项目编号

货号GTIN
D0162-100MG04061833270318
D0162-25MG04061833270325
D0162-5MG04061833270332