D0390
NG,NG ′-二甲基-L-精氨酸 二(对羟基偶氮苯对磺酸) 盐
≥99% (TLC)
别名:
SDMA
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关于此项目
经验公式（希尔记法）:
C8H18N4O2 · 2C12H10N2O4S
CAS Number:
分子量:
758.82
MDL编号:
UNSPSC代码:
12352202
PubChem化学物质编号:
NACRES:
NA.77
生物来源
synthetic (organic)
质量水平
方案
≥99% (TLC)
表单
powder
溶解性
methanol: 10 mg/mL
储存温度
room temp
SMILES字符串
CN\C(NC)=N\CCC[C@H](N)C(O)=O.Oc1ccc(cc1)\N=N\c2ccc(cc2)S(O)(=O)=O.Oc3ccc(cc3)\N=N\c4ccc(cc4)S(O)(=O)=O
InChI
1S/2C12H10N2O4S.C8H18N4O2/c2*15-11-5-1-9(2-6-11)13-14-10-3-7-12(8-4-10)19(16,17)18;1-10-8(11-2)12-5-3-4-6(9)7(13)14/h2*1-8,15H,(H,16,17,18);6H,3-5,9H2,1-2H3,(H,13,14)(H2,10,11,12)/b2*14-13+;/t;;6-/m..0/s1
InChI key
HISUXCNNXYEHER-YJSASASGSA-N
应用
血浆 对称-二甲基精氨酸一直被认为是肝、肾功能障碍的标志。开发了用于鉴别血浆和尿液样品中精氨酸和 非对称-和 对称-二甲基精氨酸的灵敏 LC-MS 方法。
血浆 对称-二甲基精氨酸一直被认为是肝、肾功能障碍的标志。开发了用于鉴别血浆和尿液样品中精氨酸和非对称和 对称二甲基精氨酸的灵敏 LC-MS 方法。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Bob Siegerink et al.
Clinical research in cardiology : official journal of the German Cardiac Society, 102(3), 193-202 (2012-10-18)
Asymmetric dimethylarginine (ADMA) is an endogenous nitric oxide synthase inhibitor, which has been associated with total and cardiovascular mortality in various clinical settings. Studies on its structural isomer, symmetric dimethylarginine (SDMA), are scarce. This study aimed to determine the associations
Lena Pelander et al.
Journal of veterinary internal medicine, 33(2), 630-639 (2019-02-23)
Early detection of decreased glomerular filtration rate (GFR) in dogs is challenging. Current methods are insensitive and new biomarkers are required. To compare overall diagnostic performance of serum symmetric dimethylarginine (SDMA) and serum cystatin C to serum creatinine, for detection
Eva Buresova et al.
Journal of veterinary internal medicine, 33(2), 516-522 (2019-01-12)
Measurement of serum creatinine (sCr) and urea nitrogen fail to detect decreased renal function in many hyperthyroid cats because of low muscle mass and glomerular hyperfiltration of affected cats. Serum symmetric dimethylarginine (sSDMA) is an earlier and more sensitive renal
Elevation of serum asymmetrical and symmetrical dimethylarginine in patients with advanced glaucoma.
Shahrbanou Javadiyan et al.
Investigative ophthalmology & visual science, 53(4), 1923-1927 (2012-03-08)
Asymmetric dimethylarginine (ADMA) and symmetric dimethylarginine (SDMA) are the dimethylated isomeric derivatives of the amino acid L-arginine. ADMA is an endogenous inhibitor of nitric oxide synthase (NOS), while SDMA is a competitive inhibitor of cellular uptake of L-arginine, the substrate
Paolo Emidio Crisi et al.
Animals : an open access journal from MDPI, 10(5) (2020-05-14)
Feline morbillivirus (FeMV) is a newly discovered paramyxovirus infecting domestic cats and its role in the pathogenesis of feline chronic kidney disease (CKD) has been suggested, however not confirmed. The primary aim of the study was to evaluate the renal
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