D103
(±)-2,3-Dichloro-α-methylbenzylamine hydrochloride
solid
别名:
DCMB, LY-78335
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关于此项目
经验公式（希尔记法）:
C8H9Cl2N · HCl
化学文摘社编号:
分子量:
226.53
UNSPSC Code:
12352202
PubChem Substance ID:
MDL number:
form
solid
color
white
solubility
H2O: soluble (Solutions may be stored for 1-2 days at 4 °C.), ethanol: soluble (Solutions may be stored for 1-2 days at 4 °C.)
SMILES string
Cl[H].CC(N)c1cccc(Cl)c1Cl
Gene Information
human ... PNMT(5409)
Biochem/physiol Actions
PNMT inhibitor.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
法规信息
新产品
此项目有
G Engberg et al.
Brain research, 223(1), 49-58 (1981-10-26)
The functional significance of the morphologically identified adrenaline (A)-mediated input to the noradrenergic nucleus locus coeruleus (LC) was pharmacologically analyzed. By means of single unit recording techniques the LC neurons in the rat brain were studied following administration of SK&F
N Y Liang et al.
The Journal of pharmacology and experimental therapeutics, 223(2), 382-387 (1982-11-01)
Intraperitoneal injections of the phenylethanolamine N-methyltransferase inhibitors 2-cyclohexyl-2-hydroxyethylamine, 1-aminomethylcycloundecanol, 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline and 2,3-dichloro-alpha-methylbenzylamine all lowered blood pressures in spontaneously hypertensive rats. The drugs did not affect the blood pressures of age-paired normotensive Wistar Kyoto rats or did the drugs alter the
S P Kalra et al.
Endocrinology, 111(4), 1403-1405 (1982-10-01)
Administration of the opiate receptor antagonist, naloxone, evoked rapid rises in plasma LH levels in estrogen, progesterone-primed ovariectomized rats. Pretreatment with a peripherally acting epinephrine (EPI) synthesis inhibitor, SK&F 29661, failed to influence the naloxone-induced LH release. However, two centrally