D1387
P1,P3-Di(adenosine-5′) triphosphate ammonium salt
solid
别名:
A(5′)P3(5′)A, Diadenosine triphosphate
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关于此项目
线性分子式:
C20H24N9O16P3 · NH3
化学文摘社编号:
分子量:
756.41
UNSPSC Code:
41106305
eCl@ss:
32160414
PubChem Substance ID:
NACRES:
NA.51
MDL number:
Form:
solid
Storage temp.:
−20°C
产品名称
P1,P3-Di(adenosine-5′) triphosphate ammonium salt,
form
solid
Quality Level
impurities
Other adenosine phosphates, essentially free
storage temp.
−20°C
SMILES string
N.Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(=O)OP(O)(=O)OCC4OC(C(O)C4O)n5cnc6c(N)ncnc56)C(O)C3O
InChI
1S/C20H27N10O16P3.H3N/c21-15-9-17(25-3-23-15)29(5-27-9)19-13(33)11(31)7(43-19)1-41-47(35,36)45-49(39,40)46-48(37,38)42-2-8-12(32)14(34)20(44-8)30-6-28-10-16(22)24-4-26-18(10)30;/h3-8,11-14,19-20,31-34H,1-2H2,(H,35,36)(H,37,38)(H,39,40)(H2,21,23,25)(H2,22,24,26);1H3
InChI key
PKSQTRWRSNNYCW-UHFFFAOYSA-N
相关类别
Application
P1,P3-Di(adenosine-5′) triphosphate ammonium salt has been used as a component of the incubation medium for incubating fibroblast cell lines for FoF1 ATP-synthase activity.
P1,P3-Di(adenosine-5′) triphosphate (Ap3A) is a diadenosine oligophosphate (ApnA) family member. ApnAs have been found to act as a signaling molecule.
Preparation Note
Approx. 25 A260 units per mg.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Dual roles of diadenosine polyphosphates in corneal epithelial cell migration
Mediero A, Peral A, Pintor J.
Investigative Ophthalmology & Visual Science, 47, 4500-4506 (2010)
Alan R Conant et al.
Vascular pharmacology, 48(4-6), 157-164 (2008-03-08)
Diadenosine polyphosphates (Ap(n)A) are released by degranulating platelets and high, local concentrations may form at sites of platelet activation. Radial artery grafts, now often used alongside the internal mammary artery in coronary artery bypass surgery, are particularly reactive to several
Brigitte Maria Stavrou
Current medicinal chemistry. Cardiovascular and hematological agents, 1(2), 151-169 (2004-08-24)
Diadenosine polyphosphates (Ap(n)A) are naturally occurring molecules which have been identified in human and guinea-pig cardiac tissue and whose physiological role is being established. They are stored in platelet dense granules in a metabolically inactive form. Ap(n)A form a class
A S Mildvan et al.
Archives of biochemistry and biophysics, 433(1), 129-143 (2004-12-08)
Nudix hydrolases catalyze the hydrolysis of nucleoside diphosphates linked to other moieties, X, and contain the sequence motif or Nudix box, GX(5)EX(7)REUXEEXGU. The mechanisms of Nudix hydrolases are highly diverse in the position on the substrate at which nucleophilic substitution
Manuela Campiglio et al.
Journal of cellular physiology, 208(2), 274-281 (2006-03-21)
FHIT is a tumor suppressor gene that is frequently inactivated in human cancer. Although the Fhit protein is known to hydrolyze diadenosine triphosphate (Ap(3)A), this hydrolase activity is not required for Fhit-mediated oncosuppression. Indeed, the molecular mechanisms and the regulatory
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| D1387-25MG | 04061833006795 |
| D1387-10MG | 04061833006788 |
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