Name: 地塞米松 21-乙酸酯
Brand: SIGMA

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About This Item

经验公式（希尔记法）:

C₂₄H₃₁FO₆

CAS Number:

1177-87-3

分子量:

434.50

Beilstein:

2342608

EC 号:

214-646-8

MDL编号:

MFCD00027407

UNSPSC代码:

51422333

PubChem化学物质编号:

24893562

NACRES:

NA.77

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Product Name

地塞米松 21-乙酸酯, ≥99%

质量水平

100

方案

≥99%

表单

powder

储存温度

2-8°C

SMILES字符串

[H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@@H](C)[C@]4(O)C(=O)COC(C)=O

InChI

1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1

InChI key

AKUJBENLRBOFTD-RPRRAYFGSA-N

基因信息

human ... NR3C1(2908)

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应用

Dexamethasone 21-acetate has been used:

as a component of the induction medium for the treatment of mice preadipocytes (5A) cells
as a synthetic glucocorticoid to study its effects on the expression of nuclear factor erythroid 2-related factor 2 (Nrf2) and peroxiredoxin 6 (Prdx6) proteins in placentas of human and mice
as a component of the complete medium for the culturing of porcine hepatocytes

生化/生理作用

Dexamethasone 21-acetate or dexamethasone acetate is a derivative of dexamethasone. It is a hydrophobic drug. Dexamethasone is a glucocorticoid possessing anti-inflammatory activity.