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Merck
CN

D1946

二氨基荧光素-FM 二乙酸酯

≥98% (HPLC), NO detector, film

别名:

4-氨基-5-(N-甲氨基)-3′,6′-双(乙酰氧基)-2′,7′-二氟-螺[ 异苯并呋喃-1 (3H) ,9′-[9H]黄原酮]-3-酮, DAF-FM DA

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关于此项目

经验公式(希尔记法):
C25H18F2N2O7
化学文摘社编号:
分子量:
496.42
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
film
Quality level:
Storage condition:
desiccated
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产品名称

二氨基荧光素-FM 二乙酸酯, ≥98% (HPLC)

SMILES string

CNc1ccc2c(c1N)C(=O)OC23c4cc(F)c(OC(C)=O)cc4Oc5cc(OC(C)=O)c(F)cc35

InChI key

BEVHTVRRVVEMEF-UHFFFAOYSA-N

InChI

1S/C25H18F2N2O7/c1-10(30)33-20-8-18-13(6-15(20)26)25(12-4-5-17(29-3)23(28)22(12)24(32)36-25)14-7-16(27)21(34-11(2)31)9-19(14)35-18/h4-9,29H,28H2,1-3H3

assay

≥98% (HPLC)

form

film

storage condition

desiccated

color

colorless to yellow

fluorescence

λex 500 nm; λem 515 nm in DMSO

shipped in

wet ice

storage temp.

−20°C

Quality Level

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Application

DAF-FM DA 已被用于测量肝组织匀浆中的一氧化氮 (NO) 水平。它还被用于检测人脐静脉内皮细胞 (HUVEC) 的 NO 染色。

Biochem/physiol Actions

DAF-FM DA 是一种用于检测一氧化氮 (NO) 的细胞渗透性荧光探针。
DAF-FM DA 是一种用于检测一氧化氮 (NO) 的细胞渗透性荧光探针。DAF-2 是最初的化合物,应用广泛,但 DAF-FM 和 DAF-FM DA 与 DAF-2 相比对一氧化氮 (NO) 更敏感,更耐光且pH 敏感性较低。DAF-FM DA 能很好地渗透到活细胞中,并通过胞浆酯酶迅速转化为水溶性 DAF-FM。

Features and Benefits

该化合物在受体分类和信号转导手册的一氧化氮合酶页面上有重点介绍。想要浏览手册的其他页面, 请单击此处

Disclaimer

吸湿

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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