D203
二丙诺啡
别名:
(5α,7α)-17-(Cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α,α-dimethyl-6,14-ethenomorphinan-7-methanol
药品控制
USDEA Schedule II; regulated under CDSA - not available from Sigma-Aldrich Canada
InChI
1S/C26H35NO4.ClH/c1-23(2,29)18-13-24-8-9-26(18,30-3)22-25(24)10-11-27(14-15-4-5-15)19(24)12-16-6-7-17(28)21(31-22)20(16)25;/h6-7,15,18-19,22,28-29H,4-5,8-14H2,1-3H3;1H/t18-,19-,22-,24?,25+,26?;/m1./s1
InChI key
UNPUINKKJUSSDZ-NNGCTRGCSA-N
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一般描述
Diprenorphine is a non-selective and an opiate receptor antagonist, that finds applications in veterinary medicine, in reversing the effects of opioid analgesics used for tranquilizing large animals.
生化/生理作用
Potent nonselective opiod antagonist.
警示用语：
Warning
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Veterinary Anesthesia and Analgesia: The Fifth Edition of Lumb and Jones (2015)
New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control (2013)
Zoo Animal and Wildlife Immobilization and Anesthesia (2014)
Y Iwasaki et al.
Endocrinology, 134(1), 48-54 (1994-01-01)
Although endogenous opioids are thought to be involved in the regulation of vasopressin secretion, their precise role is unclear. We studied the effect of the potent nonselective opioid antagonist diprenorphine on the vasopressin response to osmotic (hypertonic saline, ip), hypovolemic
Drug Discrimination: Applications to Medicinal Chemistry and Drug Studies (2011)
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