D203
二丙诺啡
别名:
(5α,7α)-17-(Cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-α,α-dimethyl-6,14-ethenomorphinan-7-methanol
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关于此项目
经验公式（希尔记法）:
C26H35NO4
化学文摘社编号:
分子量:
425.56
UNSPSC Code:
41116107
EC Number:
238-325-7
MDL number:
InChI key
UNPUINKKJUSSDZ-NNGCTRGCSA-N
InChI
1S/C26H35NO4.ClH/c1-23(2,29)18-13-24-8-9-26(18,30-3)22-25(24)10-11-27(14-15-4-5-15)19(24)12-16-6-7-17(28)21(31-22)20(16)25;/h6-7,15,18-19,22,28-29H,4-5,8-14H2,1-3H3;1H/t18-,19-,22-,24?,25+,26?;/m1./s1
drug control
USDEA Schedule II; regulated under CDSA - not available from Sigma-Aldrich Canada
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General description
Diprenorphine is a non-selective and an opiate receptor antagonist, that finds applications in veterinary medicine, in reversing the effects of opioid analgesics used for tranquilizing large animals.
Biochem/physiol Actions
Potent nonselective opiod antagonist.
signalword
Warning
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
Veterinary Anesthesia and Analgesia: The Fifth Edition of Lumb and Jones (2015)
New Trends in Radiopharmaceutical Synthesis, Quality Assurance, and Regulatory Control (2013)
Zoo Animal and Wildlife Immobilization and Anesthesia (2014)
Drug Discrimination: Applications to Medicinal Chemistry and Drug Studies (2011)
Y Iwasaki et al.
Endocrinology, 134(1), 48-54 (1994-01-01)
Although endogenous opioids are thought to be involved in the regulation of vasopressin secretion, their precise role is unclear. We studied the effect of the potent nonselective opioid antagonist diprenorphine on the vasopressin response to osmotic (hypertonic saline, ip), hypovolemic
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