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Merck
CN

D2192

Sigma-Aldrich

脱硫生物素聚氧化乙烯碘乙酰胺

≥90% (HPLC)

别名:

脱硫生物素PEO碘乙酰胺

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关于此项目

经验公式(希尔记法):
C21H38IN5O6
分子量:
583.46
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
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方案

≥90% (HPLC)

表单

powder

溶解性

H2O: 10 mg/mL

储存温度

2-8°C

SMILES字符串

CC1NC(=O)NC1CCCCCC(=O)NCCC(=O)NCCOCCOCCNC(=O)CI

InChI

1S/C21H38IN5O6/c1-16-17(27-21(31)26-16)5-3-2-4-6-18(28)23-8-7-19(29)24-9-11-32-13-14-33-12-10-25-20(30)15-22/h16-17H,2-15H2,1H3,(H,23,28)(H,24,29)(H,25,30)(H2,26,27,31)

InChI key

DBOWCCSTSCXTEL-UHFFFAOYSA-N

应用

在许多蛋白质组学类型应用(如肽图和质谱)中,半胱氨酸标记尤其有用。

特点和优势

  • 在温和条件下容易从链霉亲和素或亲和素亲和基质中洗脱
  • 包含一个16原子亲水间隔区。
  • 在pH 7.5-8.5下通常与巯基偶联

其他说明

巯基特异性水溶性生物素化试剂。

象形图

Exclamation mark

警示用语:

Warning

危险声明

预防措施声明

危险分类

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

储存分类代码

13 - Non Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Advances in proteome analysis by mass spectrometry.
T J Griffin et al.
The Journal of biological chemistry, 276(49), 45497-45500 (2001-10-05)
Michael B Goshe et al.
Journal of proteome research, 2(2), 153-161 (2003-04-29)
The ability to identify and quantitate integral membrane proteins is an analytical challenge for mass spectrometry-based proteomics. The use of surfactants to solubilize and facilitate derivatization of these proteins can suppress peptide ionization and interfere with chromatographic separations during microcapillary
T P Conrads et al.
Analytical chemistry, 73(9), 2132-2139 (2001-05-17)
We describe the combined use of 15N-metabolic labeling and a cysteine-reactive biotin affinity tag to isolate and quantitate cysteine-containing polypeptides (Cys-polypeptides) from Deinococcus radiodurans as well as from mouse B16 melanoma cells. D. radiodurans were cultured in both natural isotopic
Emily Turner-Brannen et al.
Arthritis research & therapy, 13(4), R129-R129 (2011-08-13)
Innate defence regulator (IDR) peptides are synthetic cationic peptides, variants of naturally occurring innate immune effector molecules known as host defence peptides. IDR peptides were recently demonstrated to limit infection-associated inflammation selectively without compromising host innate immune functions. This study

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