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D2396

Dimenhydrinate

Name: Dimenhydrinate
Brand: SIGMA

别名:

N-(2-Diphenylmethoxyethyl)-N,N-dimethylammonium 8-chlorotheophyllinate

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关于此项目

经验公式（希尔记法）:

C₁₇H₂₁NO · C₇H₇ClN₄O₂

化学文摘社编号:

523-87-5

分子量:

469.96

NACRES:

NA.77

PubChem Substance ID:

329798738

UNSPSC Code:

41116107

EC Number:

208-350-8

MDL number:

MFCD00054265

Form:

powder

Quality level:

100

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form

powder

Quality Level

100

SMILES string

CN1C(=O)N(C)c2nc(Cl)[nH]c2C1=O.CN(C)CCOC(c3ccccc3)c4ccccc4

InChI

1S/C17H21NO.C7H7ClN4O2/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;1-11-4-3(9-6(8)10-4)5(13)12(2)7(11)14/h3-12,17H,13-14H2,1-2H3;1-2H3,(H,9,10)

InChI key

NFLLKCVHYJRNRH-UHFFFAOYSA-N

Gene Information

human ... HRH1(3269)

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General description

Dimenhydrinate is a salt of antihistamine drugs, such as diphenhydramine and 8-chlorotheophylline. It has antiemetic properties. Dimenhydrinate is used to treat nausea and vomiting during pregnancy.

pictograms

GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

ppe

dust mask type N95 (US), Eyeshields, Gloves

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Oral dimenhydrinate versus placebo in children with gastroenteritis: a randomized controlled trial.

Serge Gouin et al.

Pediatrics, 129(6), 1050-1055 (2012-05-16)

To evaluate the efficacy and safety of oral dimenhydrinate in the treatment of acute gastroenteritis. This was a randomized, double-blind, placebo-controlled trial conducted in the emergency department of a pediatric university-affiliated center. Children 1 to 12 years old who presented

Photoelectron spectroscopic study of the hydrated nucleoside anions: Uridine(-)(H(2)O)(n=0-2), cytidine(-)(H(2)O)(n=0-2), and thymidine(-)(H(2)O)(n=0,1).

Xiang Li et al.

The Journal of chemical physics, 133(14), 144304-144304 (2010-10-19)

The hydrated nucleoside anions, uridine(-)(H(2)O)(n=0-2), cytidine(-)(H(2)O)(n=0-2), and thymidine(-)(H(2)O)(n=0,1), have been prepared in beams and studied by anion photoelectron spectroscopy in order to investigate the effects of a microhydrated environment on parent nucleoside anions. Vertical detachment energies (VDEs) were measured for

Ventricular tachycardia after ondansetron administration in a child with undiagnosed long QT syndrome.

Kyle McKechnie et al.

Canadian journal of anaesthesia = Journal canadien d'anesthesie, 57(5), 453-457 (2010-03-06)

To describe a case of ventricular tachycardia after co-administration of ondansetron and dimenhydrinate to a child with occult congenital QT prolongation. A previously healthy 11-yr-old girl presented for surgical excision of a thyroglossal duct cyst under general anesthesia. Induction and

Direct standard-free quantitation of Tamiflu and other pharmaceutical tablets using clustering agents with electrospray ionization mass spectrometry.

Tawnya G Flick et al.

Analytical chemistry, 82(4), 1179-1182 (2010-01-23)

Accurate and rapid quantitation is advantageous to identify counterfeit and substandard pharmaceutical drugs. A standard-free electrospray ionization mass spectrometry method is used to directly determine the dosage in the prescription and over-the-counter drugs Tamiflu, Sudafed, and Dramamine. A tablet of

Drugs During Pregnancy and Lactation: Handbook of Prescription Drugs and Comparative Risk Assessment (2001)

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全球贸易项目编号

货号	GTIN
D2396-10G	04061833562154

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