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文件

D2510

Sigma-Aldrich

脱氧胆酸

≥98% (HPLC)

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别名:
3α,12α-二羟基-5β-胆甾烯酸, 7-脱氧胆酸, 脱氧胆酸
经验公式（希尔记法）:
C24H40O4
CAS号:
83-44-3
分子量:
392.57
Beilstein:
3219882
EC 号:
201-478-5
MDL编号:
MFCD00003673
PubChem化学物质编号:
24893692

生物来源

bovine bile (ex gall bladder)

质量水平

200

描述

anionic

检测方案

≥98% (HPLC)

形式

powder

分子量

392.57 g/mol

mp

171-174 °C (lit.)

官能团

carboxylic acid

运输

ambient

储存温度

room temp

SMILES string

C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C

InChI

1S/C24H40O4/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3/h14-21,25-26H,4-13H2,1-3H3,(H,27,28)/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-/m1/s1

InChI key

KXGVEGMKQFWNSR-LLQZFEROSA-N

Gene Information

human ... ATIC(471)

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相关类别

一般描述

脱氧胆酸是一种促炎剂。

应用

脱氧胆酸已被用于评估在癌性环境下，脱氧胆酸和叶酸共改性壳聚糖胶束的 pH 响应机制。 它还被用于研究熊去氧胆酸在实验性结肠炎中的剂量依赖性抗炎作用。

生化/生理作用

胆汁酸

象形图

Exclamation mark
GHS07

警示用语：

Warning

危险分类

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves

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实验方案

Fast and Robust HPLC Separation of Bile Acids and Conjugates with Ascentis Express C18

This method is particularly useful in research into the role of individual bile acids as signaling molecules; suitable for clinical laboratories to investigate potential mechanisms linked to gut hormone profiles and glycemic control.

相关内容

Bile Acids Kit for LC-MS

Bile Acids (BA) are synthesized in the liver and play important roles in cholesterol homeostasis, absorption of vitamins and lipids, and various key metabolic processes.

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