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Merck
CN

D2625

丹磺酰氯

BioReagent, suitable for amino acid labeling, powder and chunks, ≥99% (HPLC)

别名:

5-（二甲基氨基）-萘-1-磺酰氯, DNSCl

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关于此项目

经验公式（希尔记法）:
C12H12ClNO2S
化学文摘社编号:
605-65-2
分子量:
269.75
UNSPSC Code:
12352101
NACRES:
NA.26
PubChem Substance ID:
24893700
EC Number:
210-092-6
Beilstein/REAXYS Number:
2217205
MDL number:
MFCD00003985

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产品名称

丹磺酰氯, BioReagent, suitable for amino acid labeling, powder and chunks, ≥99% (HPLC)

InChI key

XPDXVDYUQZHFPV-UHFFFAOYSA-N

InChI

1S/C12H12ClNO2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3

SMILES string

CN(C)c1cccc2c(cccc12)S(Cl)(=O)=O

product line

BioReagent

assay

≥99% (HPLC)

form

powder and chunks

color

yellow to yellow-orange

mp

72-74 °C (lit.)

solubility

acetone: 20 mg/mL

suitability

suitable for amino acid labeling

storage temp.

2-8°C

Quality Level

200

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Application

一种用于氨基酸和肽的荧光N-末端衍生化的荧光试剂，并且可用反相HPLC进行检测。
丹磺酰氯已用于：
  • 用作一种荧光试剂，荧光N末端衍生化氨基酸和多肽，并通过反相高效液相色谱（HPLC）检测
  • 衍生化血浆样品
  • 定量固定化碱性磷酸酶

Biochem/physiol Actions

丹磺酰氯是磺酰氯化合物。它用于末端标记肽和蛋白质的氨基。丹磺酰氯用于在神经样品和生物体液中衍生游离氨基酸和胺。它用于研究白蛋白荧光复合物、蛋白质构象变化研究和活性位点鉴定。

pictograms

Corrosion
GHS05

signalword

Danger

hcodes

H290,H314

Hazard Classifications

Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B

存储类别

8A - Combustible corrosive hazardous materials

wgk

WGK 3

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
BCCN1165
BCCM9498
BCCL1089
BCCH0297
BCCG9444

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Simultaneous separation and quantitation of amino acids and polyamines of forest tree tissues and cell cultures within a single high-performance liquid chromatography run using dansyl derivatization
Minocha R and Long S
Journal of Chromatography A, 1035(1), 63-73 (2004)
Covalent protein immobilization on glass surfaces: Application to alkaline phosphatase
Taylor RH, et al.
Journal of Biotechnology, 118(3), 265-269 (2005)
The use of dansyl-chloride for the detection of amino acids and serotonin in nervous tissue
Research Methods in Neurochemistry, 443-462 (1975)
Measuring the poise of thiol/disulfide couples in vivo
Jones DP and Liang Y
Free radical biology & medicine, 47(10), 1329-1338 (2009)
V Konakovsky et al.
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment, 28(4), 408-416 (2011-02-22)
Biogenic amines in wine may impair sensory wine quality and cause adverse health effects in susceptible individuals. In this study, histamine and other biogenic amines were determined by HPLC after amine derivatisation to dansyl chloride conjugates in 100 selected high-quality
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