D2779
双十八烷基二甲基溴化铵
≥98% (TLC)
别名:
二甲基二(十八烷基)溴化铵
描述
cationic
质量水平
方案
≥98% (TLC)
表单
powder
分子量
630.95 g/mol
mp
~160 °C
应用
cell analysis
SMILES字符串
CCCCCCCCCCCCCCCCCC[N+](CCCCCCCCCCCCCCCCCC)(C)C.[Br-]
InChI
1S/C38H80N.BrH/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-39(3,4)38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2;/h5-38H2,1-4H3;1H/q+1;/p-1
InChI key
PSLWZOIUBRXAQW-UHFFFAOYSA-M
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一般描述
二甲基双十八烷基溴化铵是一种阳离子脂质，可刺激免疫反应，激活巨噬细胞，并与抗原结合。
应用
二甲基双十八烷基溴化铵已用于一项研究，使用镜面反射中子反射、表面压力-面积等温线和布鲁斯特角显微镜评估其单层与 DNA 的相互作用。 也用于研究用于牛病毒性腹泻病毒 (BVDV) 灭活疫苗的新佐剂。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
F S Baechtel et al.
Cancer research, 42(12), 4959-4963 (1982-12-01)
Dimethyldioctadecylammonium bromide (DDA) stimulates immune responses, primes (or activates) macrophages, and binds to antigens. Because relatively little is known about the binding of adjuvants to antigens, the nature of the interaction of DDA with soluble protein and cellular antigens was
Julia F Ridpath et al.
Veterinary research communications, 34(8), 691-702 (2010-09-28)
Bovine viral diarrhea virus (BVDV) infections cause respiratory, reproductive, and enteric disease in cattle. Vaccination raises herd resistance and limits the spread of BVDV among cattle. Both killed and modified live vaccines against BVDV are available. While modified live vaccines
Paolo Sabatino et al.
The journal of physical chemistry. B, 116(30), 9269-9276 (2012-06-27)
The interaction between phenol molecules, both in their undissociated and dissociated states, and cationic dioctadecyl dimethylammonium chloride (DODAC) vesicles were thoroughly investigated using NMR techniques. In particular, diffusion and relaxation measurements, combined with the two sites Kärger model, were used
Zhi Rao et al.
Colloids and surfaces. B, Biointerfaces, 97, 248-253 (2012-05-23)
In order to confirm that the cholesterol end groups of cholesterol-end capped polyethylene glycol really insert into the liposome bilayer and investigate how the incorporation affects the microenvironment of liposome bilayer, two kinds of molecular probes, namely Nile Red and
Randip Kaur et al.
Journal of controlled release : official journal of the Controlled Release Society, 158(1), 72-77 (2011-10-29)
The adjuvant efficacy of cationic liposomes composed of dimethyldioctadecylammonium bromide and trehalose dibehenate (DDA:TDB) is well established. Whilst the mechanism behind its immunostimulatory action is not fully understood, the ability of the formulation to promote a 'depot effect' is a
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