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Merck
CN

D2779

双十八烷基二甲基溴化铵

≥98% (TLC)

别名:

二甲基二(十八烷基)溴化铵

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关于此项目

线性分子式:
[CH3(CH2)17]2N(Br)(CH3)2
化学文摘社编号:
分子量:
630.95
Beilstein:
3580323
EC 号:
MDL编号:
UNSPSC代码:
12161900
PubChem化学物质编号:
NACRES:
NA.25
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描述

cationic

质量水平

方案

≥98% (TLC)

表单

powder

分子量

630.95 g/mol

mp

~160 °C

应用

cell analysis

SMILES字符串

CCCCCCCCCCCCCCCCCC[N+](CCCCCCCCCCCCCCCCCC)(C)C.[Br-]

InChI

1S/C38H80N.BrH/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-39(3,4)38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2;/h5-38H2,1-4H3;1H/q+1;/p-1

InChI key

PSLWZOIUBRXAQW-UHFFFAOYSA-M

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一般描述

二甲基双十八烷基溴化铵是一种阳离子脂质,可刺激免疫反应,激活巨噬细胞,并与抗原结合。

应用

二甲基双十八烷基溴化铵已用于一项研究,使用镜面反射中子反射、表面压力-面积等温线和布鲁斯特角显微镜评估其单层与 DNA 的相互作用。 也用于研究用于牛病毒性腹泻病毒 (BVDV) 灭活疫苗的新佐剂。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

dust mask type N95 (US), Eyeshields, Gloves


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Julia F Ridpath et al.
Veterinary research communications, 34(8), 691-702 (2010-09-28)
Bovine viral diarrhea virus (BVDV) infections cause respiratory, reproductive, and enteric disease in cattle. Vaccination raises herd resistance and limits the spread of BVDV among cattle. Both killed and modified live vaccines against BVDV are available. While modified live vaccines
F S Baechtel et al.
Cancer research, 42(12), 4959-4963 (1982-12-01)
Dimethyldioctadecylammonium bromide (DDA) stimulates immune responses, primes (or activates) macrophages, and binds to antigens. Because relatively little is known about the binding of adjuvants to antigens, the nature of the interaction of DDA with soluble protein and cellular antigens was
A P Dabkowska et al.
Biomacromolecules, 13(8), 2391-2401 (2012-06-26)
The interaction of DNA with monolayers of the cationic lipid dimethyldioctadecylammonium bromide, with/without 50 mol % of a neutral "helper" lipid, either dioleoylphosphatidylethanolamine or cholesterol, has been studied using specular neutron reflection, surface pressure-area isotherms, and Brewster angle microscopy. The
Julio H K Rozenfeld et al.
Journal of controlled release : official journal of the Controlled Release Society, 160(2), 367-373 (2011-11-01)
The cationic lipid dioctadecyldimethylammonium bromide (DODAB) and the CpG oligonucleotide (CpG) have been separately used as potent immunoadjuvants driving Th1 responses. Here DODAB bilayer fragments (BF) and CpG (5'-TTGACGTTCG-3') assemblies have their physical properties and immunoadjuvant activity determined using ovalbumin
Deepesh Bhardwaj et al.
Journal of hazardous materials, 227-228, 292-300 (2012-06-12)
This article introduces the synthesis of clinoptilolite and montmorillonite, and their surfactant modification by using solutions of hexadecyltrimethylammonium bromide (CH(3)(CH(2))(15)N(Br)(CH(3))(3), HDTMAB) and dioctadecyldimethylammonium bromide ((CH(3)(CH(2))(17))(2)N(Br)(CH(3))(2), DODMAB). The feasibility of using surfactant modified silicates (SMSs) as a potential adsorbent for nitrate

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