D2779
双十八烷基二甲基溴化铵
≥98% (TLC)
别名:
二甲基二(十八烷基)溴化铵
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关于此项目
线性分子式:
[CH3(CH2)17]2N(Br)(CH3)2
化学文摘社编号:
分子量:
630.95
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
EC Number:
223-037-6
Beilstein/REAXYS Number:
3580323
MDL number:
产品名称
双十八烷基二甲基溴化铵, ≥98% (TLC)
InChI
1S/C38H80N.BrH/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-39(3,4)38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2;/h5-38H2,1-4H3;1H/q+1;/p-1
InChI key
PSLWZOIUBRXAQW-UHFFFAOYSA-M
SMILES string
CCCCCCCCCCCCCCCCCC[N+](CCCCCCCCCCCCCCCCCC)(C)C.[Br-]
description
cationic
assay
≥98% (TLC)
form
powder
mol wt
630.95 g/mol
mp
~160 °C
application(s)
cell analysis
Quality Level
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Application
二甲基双十八烷基溴化铵已用于一项研究，使用镜面反射中子反射、表面压力-面积等温线和布鲁斯特角显微镜评估其单层与 DNA 的相互作用。 也用于研究用于牛病毒性腹泻病毒 (BVDV) 灭活疫苗的新佐剂。
General description
二甲基双十八烷基溴化铵是一种阳离子脂质，可刺激免疫反应，激活巨噬细胞，并与抗原结合。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
F S Baechtel et al.
Cancer research, 42(12), 4959-4963 (1982-12-01)
Dimethyldioctadecylammonium bromide (DDA) stimulates immune responses, primes (or activates) macrophages, and binds to antigens. Because relatively little is known about the binding of adjuvants to antigens, the nature of the interaction of DDA with soluble protein and cellular antigens was
Julia F Ridpath et al.
Veterinary research communications, 34(8), 691-702 (2010-09-28)
Bovine viral diarrhea virus (BVDV) infections cause respiratory, reproductive, and enteric disease in cattle. Vaccination raises herd resistance and limits the spread of BVDV among cattle. Both killed and modified live vaccines against BVDV are available. While modified live vaccines
Paolo Sabatino et al.
The journal of physical chemistry. B, 116(30), 9269-9276 (2012-06-27)
The interaction between phenol molecules, both in their undissociated and dissociated states, and cationic dioctadecyl dimethylammonium chloride (DODAC) vesicles were thoroughly investigated using NMR techniques. In particular, diffusion and relaxation measurements, combined with the two sites Kärger model, were used
A P Dabkowska et al.
Biomacromolecules, 13(8), 2391-2401 (2012-06-26)
The interaction of DNA with monolayers of the cationic lipid dimethyldioctadecylammonium bromide, with/without 50 mol % of a neutral "helper" lipid, either dioleoylphosphatidylethanolamine or cholesterol, has been studied using specular neutron reflection, surface pressure-area isotherms, and Brewster angle microscopy. The
Randip Kaur et al.
Journal of controlled release : official journal of the Controlled Release Society, 158(1), 72-77 (2011-10-29)
The adjuvant efficacy of cationic liposomes composed of dimethyldioctadecylammonium bromide and trehalose dibehenate (DDA:TDB) is well established. Whilst the mechanism behind its immunostimulatory action is not fully understood, the ability of the formulation to promote a 'depot effect' is a
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