D3415
双酚 A 二缩水甘油醚
viscous liquid, PPARγ inhibitor
别名:
2,2-二[4-(氧化缩水甘油)苯基]丙烷, 4,4′-异亚丙基联苯酚二缩水甘油醚, BADGE, D.E.R.™ 332
产品名称
双酚 A 二缩水甘油醚,
表单
viscous liquid
质量水平
组成
Epoxide equivalent weight, 172-176
密度
1.16 g/mL at 25 °C (lit.)
SMILES字符串
CC(C)(c1ccc(OCC2CO2)cc1)c3ccc(OCC4CO4)cc3
InChI
1S/C21H24O4/c1-21(2,15-3-7-17(8-4-15)22-11-19-13-24-19)16-5-9-18(10-6-16)23-12-20-14-25-20/h3-10,19-20H,11-14H2,1-2H3
InChI key
LCFVJGUPQDGYKZ-UHFFFAOYSA-N
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一般描述
双酚A二缩水甘油醚是一种环氧树脂。
应用
双酚A二缩水甘油醚已用于：
- 研究其对阿黑皮素原(POMC)的作用：增强转基因鱼中的绿色荧光蛋白(EGFP)表达
- 研究环氧/聚酰胺—胺体系的固化行为、动力学和掺入Fe3O4磁性纳米颗粒(MNPs)的影响
- 作为热固性树脂
- 确定环氧-聚硅氧烷共混物的最佳配比
- 制备环氧树脂纳米复合涂层
- 用于石墨烯/环氧树脂(E/G)的制备、涂布和固化
生化/生理作用
PPARγ 抑制剂可阻断罗格列酮和胰岛素诱导的脂肪形成。
其他说明
环氧树脂通常与 DER 732 一起使用，形成不同强度和硬度的团块。
法律信息
D.E.R. is a trademark of The Dow Chemical Company or an affiliated company of Dow
警示用语：
Warning
危险分类
Aquatic Chronic 2 - Eye Irrit. 2 - Skin Irrit. 2 - Skin Sens. 1
储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
507.2 - 514.4 °F - closed cup
闪点(°C)
264 - 268 °C - closed cup
个人防护装备
Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter
Hoa H Le et al.
Endocrinology, 151(12), 5689-5699 (2010-10-12)
Estrogenic endocrine disrupting chemicals (EDCs) constitute a diverse group of man-made chemicals and natural compounds derived from plants and microbial metabolism. Estrogen-like actions are mediated via the nuclear hormone receptor activity of estrogen receptor (ER)α and ERβ and rapid regulation
Design and Manufacture of Textile Composites (2005)
Enhanced Charpy impact strength of epoxy resin modified with vinyl-terminated polydimethylsiloxane
Vilcakova J, et al.
Journal of Applied Polymer Science, 135(4), 45720-45720 (2018)
H M Wright et al.
The Journal of biological chemistry, 275(3), 1873-1877 (2000-01-15)
While searching for natural ligands for the peroxisome proliferator-activated receptor (PPAR) gamma, we identified a synthetic compound that binds to this receptor. Bisphenol A diglycidyl ether (BADGE) is a ligand for PPARgamma with a K(d(app)) of 100 microM. This compound
Transparent nanocomposite coatings based on epoxy and layered double hydroxide: nonisothermal cure kinetics and viscoelastic behavior assessments
Rastin H, et al.
Progress in Organic Coatings, 113, 126-135 (2017)
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