D3648
二酰胺
别名:
1,1′-偶氮二（N，N二甲基甲酰胺）, N,N,N′,N′-四甲基偶氮二甲酰胺, TMAD, 二氮杂二羧酸双（N，N-二甲基酰胺）, 偶氮二羧酸双（二甲基酰胺）
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关于此项目
线性分子式:
(CH3)2NCON=NCON(CH3)2
化学文摘社编号:
分子量:
172.19
Beilstein:
1910409
EC 号:
MDL编号:
UNSPSC代码:
12352102
PubChem化学物质编号:
NACRES:
NA.22
应用
据报道可用作巯基氧化剂。二酰胺已被用于对蛋白质谷胱甘肽化进行滴定，以区分其他氧化蛋白质修饰。该处理以浓度依赖性的方式增加蛋白质谷胱甘肽化，并且对蛋白与蛋白之间二硫化物的形成具有相对较小的影响。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Bradford G Hill et al.
Biochimica et biophysica acta, 1797(2), 285-295 (2009-11-21)
Protein thiolation by glutathione is a reversible and regulated post-translational modification that is increased in response to oxidants and nitric oxide. Because many mitochondrial enzymes contain critical thiol residues, it has been hypothesized that thiolation reactions regulate cell metabolism and
Carlos A Sorgi et al.
Scientific reports, 7(1), 10981-10981 (2017-09-10)
The differentiation of resident tissue macrophages from embryonic precursors and that of inflammatory macrophages from bone marrow cells leads to macrophage heterogeneity. Further plasticity is displayed through their ability to be polarized as subtypes M1 and M2 in a cell
Yong Tao et al.
Insect biochemistry and molecular biology, 43(9), 820-828 (2013-06-29)
Anthranilic diamides, which include the new commercial insecticide, chlorantraniliprole, are an exciting new class of chemistry that target insect ryanodine receptors. These receptors regulate release of stored intracellular calcium and play a critical role in muscle contraction. As with insects
Dierk-Christoph Pöther et al.
International journal of medical microbiology : IJMM, 303(3), 114-123 (2013-03-23)
Bacillithiol (Cys-GlcN-malate, BSH) serves as a major low molecular weight thiol in low GC Gram-positive bacteria including Bacillus species and a variety of Staphylococcus aureus strains. These bacteria do not produce glutathione (GSH). In this study, HPLC analyses were used
Yumei He et al.
Nucleic acids research, 45(1), 106-114 (2016-09-25)
We describe a Pap1-Oxs1 pathway for diamide-induced disulfide stress in Schizosaccharomyces pombe, where the nucleocytoplasmic HMG protein Oxs1 acts cooperatively with Pap1 to regulate transcription. Oxs1 and Pap1 form a complex when cells are exposed to diamide or Cd that
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