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Merck
CN

D3676

10-脱乙酰基巴卡汀III 来源于浆果紫杉

≥95% (HPLC)

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关于此项目

经验公式（希尔记法）:
C29H36O10
化学文摘社编号:
32981-86-5
分子量:
544.59
NACRES:
NA.85
PubChem Substance ID:
24893778
UNSPSC Code:
51102829
MDL number:
MFCD00132913

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产品名称

10-脱乙酰基巴卡汀III 来源于浆果紫杉, ≥95% (HPLC)

InChI

1S/C29H36O10/c1-14-17(31)12-29(36)24(38-25(35)16-9-7-6-8-10-16)22-27(5,23(34)21(33)20(14)26(29,3)4)18(32)11-19-28(22,13-37-19)39-15(2)30/h6-10,17-19,21-22,24,31-33,36H,11-13H2,1-5H3/t17-,18-,19+,21+,22-,24-,27+,28-,29+/m0/s1

SMILES string

[H][C@@]12C[C@H](O)[C@@]3(C)C(=O)[C@H](O)C4=C(C)[C@@H](O)C[C@@](O)([C@@H](OC(=O)c5ccccc5)[C@]3([H])[C@@]1(CO2)OC(C)=O)C4(C)C

InChI key

YWLXLRUDGLRYDR-ZHPRIASZSA-N

biological source

Taxus baccata

assay

≥95% (HPLC)

form

solid

mol wt

544.59 g/mol

color

white

solubility

methanol: soluble, clear, colorless (5 mg + 0.1 mL MeOH)

antibiotic activity spectrum

neoplastics

mode of action

DNA synthesis | interferes

storage temp.

2-8°C

Quality Level

200

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相关类别

Application

10-脱乙酰基浆果赤霉素III被用作制备抗癌药物紫杉醇（紫杉醇）的一种化学中间体。它被用于研究紫杉醇生物合成途径。

Biochem/physiol Actions

10-脱乙酰基浆果赤霉素III是紫杉醇生物合成的第五中间体。该生物合成通路由大约20个尚未被完全阐明的酶促步骤组成。

pictograms

Health hazardExclamation mark
GHS08,GHS07

signalword

Danger

Hazard Classifications

Carc. 1B - Eye Irrit. 2 - Muta. 1B - Skin Irrit. 2 - STOT RE 2 - STOT SE 3

target_organs

Respiratory system

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000448018
0000448018
0000360449
0000360449
SLBD3989V

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