D4001
2′-脱氧尿苷 5′-三磷酸 钠盐
≥95%
别名:
dUTP 钠盐
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关于此项目
经验公式（希尔记法）:
C9H15N2O14P3 · xNa+
化学文摘社编号:
分子量:
468.14 (free acid basis)
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
产品名称
2′-脱氧尿苷 5′-三磷酸 钠盐, ≥95%
InChI
1S/C9H15N2O14P3.Na.H/c12-5-3-8(11-2-1-7(13)10-9(11)14)23-6(5)4-22-27(18,19)25-28(20,21)24-26(15,16)17;;/h1-2,5-6,8,12H,3-4H2,(H,18,19)(H,20,21)(H,10,13,14)(H2,15,16,17);;
SMILES string
[Na].OC1CC(OC1COP(O)(=O)OP(O)(=O)OP(O)(O)=O)N2C=CC(=O)NC2=O
InChI key
FVFWWPFKJNTHIQ-UHFFFAOYSA-N
biological source
synthetic (organic)
assay
≥95%
form
powder
storage temp.
−20°C
Quality Level
相关类别
Application
2′-脱氧尿苷5′-三磷酸钠盐已用于从非洲cat鱼中提取白肌肉。
2′-脱氧尿苷5′-三磷酸（dUTP）可用于研究脱氧尿苷5′-三磷酸核苷酸水解酶（dUTPase，EC 3.6.1.23）的分布，特异性和动力学。dUTPase是保护细胞免受dUTP掺入DNA的重要酶。dUTP是TUNEL（末端脱氧核糖核苷酸转移酶（TdT）介导的脱氧尿苷-5′-三磷酸（dUTP）缺口末端标记）测试的组成部分。TUNEL是检测凋亡信号级联反应导致的DNA片段化的常用方法。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Lucy Freeman et al.
The Journal of biological chemistry, 284(37), 25280-25289 (2009-07-10)
Deoxyuridine 5'-triphosphate pyrophosphatases (dUTPases) are ubiquitous enzymes essential for hydrolysis of dUTP, thus preventing its incorporation into DNA. Although Epstein-Barr virus (EBV) dUTPase is monomeric, it has a high degree of similarity with the more frequent trimeric form of the
Claudia Ulbrich et al.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 26(6), 1011-1022 (2011-01-12)
Myocardium is very sensitive to gravitational changes. During a spaceflight cardiovascular atrophy paired with rhythm problems and orthostatic intolerance can occur. The aim of this study was to investigate the impact of basic fibroblast growth factor (bFGF) and vascular endothelial
Kwou-Yeung Wu et al.
Molecular vision, 14, 1705-1712 (2008-09-23)
Previous studies have indicated that improper use of mitomycin C (MMC) caused cytotoxicity in corneal endothelial cells. The aim of the present study was to investigate whether MMC induces cellular apoptosis in corneal endothelial cells and to determine the mechanism
Alexandra Kalogeraki et al.
Acta cytologica, 54(1), 39-42 (2010-03-24)
To evaluate apoptosis and cell proliferation on cytologic specimens (smears) from endoscopic retrograde cholangiopancreatography in patients with ampulary carcinoma and to correlate that relationship with the grade of the tumors. Forty patients (23 males and 17 females) aged 45-81 who
Dietary canitine maintains energy reserves and delays fatigue of exercised african catfish (Clarias gariepinus) fed high fat diets
Ozorio R, et al.
Scientia Agricola, 62(3), 208-213 (2005)
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