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Merck
CN

D4543

16,16-二甲基前列腺素 E2

methyl acetate solution

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关于此项目

经验公式(希尔记法):
C22H36O5
化学文摘社编号:
分子量:
380.52
UNSPSC Code:
12352200
MDL number:
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InChI key

QAOBBBBDJSWHMU-WMBBNPMCSA-N

InChI

1S/C22H36O5/c1-4-5-14-22(2,3)20(25)13-12-17-16(18(23)15-19(17)24)10-8-6-7-9-11-21(26)27/h6,8,12-13,16-17,19-20,24-25H,4-5,7,9-11,14-15H2,1-3H3,(H,26,27)/b8-6-,13-12+/t16-,17-,19-,20-/m1/s1

SMILES string

CCCCC(C)(C)[C@H](O)\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1C\C=C/CCCC(O)=O

form

methyl acetate solution

shipped in

wet ice

storage temp.

−20°C

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Other Notes

Similar to D 0160, but produced by Sigma.

pictograms

FlameExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Flam. Liq. 2 - STOT SE 3

target_organs

Central nervous system

supp_hazards

存储类别

3 - Flammable liquids

wgk

WGK 2

flash_point_f

8.6 °F

flash_point_c

-13 °C

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

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Lot/Batch Number

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Marco Failla et al.
American journal of respiratory cell and molecular biology, 41(1), 50-58 (2008-12-09)
In this study, we evaluated the protective effect and therapeutic potential of the prostaglandin E(2) (PGE(2)) synthetic analog 16,16-dimethyl-PGE(2) (dmPGE(2)) in the animal model of pulmonary fibrosis induced by bleomycin. Mice subjected to intratracheal administration of bleomycin (1 mg/kg) received
Brigitta M Peskar et al.
The Journal of pharmacology and experimental therapeutics, 301(3), 969-974 (2002-05-23)
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