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D4641

正十二烷基β-D-麦芽糖苷

≥98% (GC)

别名:

DDM, 月桂基-β-D-麦芽糖苷

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关于此项目

经验公式（希尔记法）:
C24H46O11
化学文摘社编号:
69227-93-6
分子量:
510.62
NACRES:
NA.25
PubChem Substance ID:
24893890
eCl@ss:
32190102
UNSPSC Code:
12161900
MDL number:
MFCD00043012
Beilstein/REAXYS Number:
55318
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biological source

corn

Quality Level

200

description

non-ionic

assay

≥98% (GC)

form

powder

mol wt

micellar avg mol wt 50,000

aggregation number

98

technique(s)

protein quantification: suitable

impurities

<1.5% water (Karl Fischer)

CMC

0.15 mM (20-25°C)

mp

224-226 °C (lit.)

solubility

water: 50 mg/mL, clear to very slightly hazy, colorless

storage temp.

−20°C

SMILES string

CCCCCCCCCCCCO[C@@H]1O[C@H](CO)[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O

InChI

1S/C24H46O11/c1-2-3-4-5-6-7-8-9-10-11-12-32-23-21(31)19(29)22(16(14-26)34-23)35-24-20(30)18(28)17(27)15(13-25)33-24/h15-31H,2-14H2,1H3/t15-,16-,17-,18+,19-,20-,21-,22-,23-,24-/m1/s1

InChI key

NLEBIOOXCVAHBD-QKMCSOCLSA-N

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General description

十二烷基-β-D-麦芽糖苷(N-dodecyl-β-D-maltoside)也称为月桂酰基麦芽糖苷，是一种非离子型表面活性剂和芘(Py)衍生物。作为烷基麦芽吡喃糖苷去污剂，对膜蛋白的溶解和结晶效用优异，是细胞生物学和生物化学研究的重要工具。它的独特性在于容易形成类似膜环境的胶束，从而维持膜结合蛋白的α-螺旋结构和天然构象。

十二烷基-β-D-麦芽糖苷还有其他多种用途，包括纯化和稳定RNA聚合酶、检测蛋白-脂质互作、作为糖原蛋白(glycogenin)催化葡萄糖基和木糖苷转移的底物。温和、非变性的特性适合蛋白-麻醉研究。总而言之，十二烷基-β-D-麦芽糖苷是一种多功能的去污剂，在膜蛋白等研究领域应用广泛。它维持蛋白结构和功能的重要特性令其成为膜生物学精细探索不可或缺的工具。

Application

正十二烷基β-D-麦芽糖甙已被用于一项研究，以评估通过GPS-NMR和散射技术映射整体螺旋膜蛋白的展开状态。
非离子型去污剂，用于提取和溶解蛋白质。
非离子型去污剂，用于酶的稳定和活化以及用于膜研究。

Features and Benefits

  • 功能丰富的表面活性剂，适于细胞生物学和生物化学研究
  • 适于蛋白定量

Other Notes

如需了解生化试剂系列的更多信息，请填写此表。

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

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分析证书(COA)

Lot/Batch Number
0000551024
0000534234
0000534233
0000551024
0000542402

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实验方案

Solubilization of Membrane Proteins

This page shows how to solubilize membrane proteins with products from Cytiva.

全球贸易项目编号

货号GTIN
D4641-1G04061833565582
D4641-5G04061833565704
D4641-25G04061835512430
D4641-10MG04061832888453
D4641-500MG04061833565599

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