Destruxin A from Metarrhizium anisopliae

Name: Destruxin A from <I>Metarrhizium anisopliae</I>
Brand: SIGMA

≥98% (HPLC)

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所有图片(1)

About This Item

经验公式（希尔记法）:

C₂₉H₄₇N₅O₇

CAS Number:

6686-70-0

分子量:

577.71

MDL编号:

MFCD01736100

UNSPSC代码:

12352200

PubChem化学物质编号:

329798802

NACRES:

NA.32

生物来源

Metarrhizium anisopliae

质量水平

200

方案

≥98% (HPLC)

表单

powder

储存温度

−20°C

SMILES字符串

CC[C@H](C)[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@H](CC=C)OC(=O)CCNC(=O)[C@H](C)N(C)C(=O)[C@H](C(C)C)N(C)C1=O

InChI

1S/C29H47N5O7/c1-9-12-21-27(38)34-16-11-13-20(34)26(37)31-23(18(5)10-2)28(39)33(8)24(17(3)4)29(40)32(7)19(6)25(36)30-15-14-22(35)41-21/h9,17-21,23-24H,1,10-16H2,2-8H3,(H,30,36)(H,31,37)/t18-,19-,20+,21-,23-,24-/m0/s1

InChI key

XIYSEKITPHTMJT-UTJJDKHZSA-N

应用

Destruxin A from Metarrhizium anisopliae has been used for immersion and inoculation bioassay in Rhipicephalus (Boophilus) microplus. It has been used as a transport inhibitor in Drosophila melanogaster.

生化/生理作用

Destruxin A is a cyclic hexadepsipeptide produced by fungus causing paralysis and death in insects. May suppress the insect immune response. Possesses an inhibitory activity on leukemic cell proliferation, decreasing the number of cells in G₂/M phase. It is virustatic against arboviruses.