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D5155

双氢链霉素倍半硫酸酯

Name: 双氢链霉素 倍半硫酸酯
Brand: SIGMA

powder, suitable for cell culture, BioReagent

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关于此项目

线性分子式:

C₂₁H₄₁N₇O₁₂ · 3/2H₂SO₄

化学文摘社编号:

5490-27-7

分子量:

730.71

NACRES:

NA.76

PubChem Substance ID:

24893928

UNSPSC Code:

12352207

EC Number:

226-823-7

MDL number:

MFCD00070252

Beilstein/REAXYS Number:

3894221

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产品名称

双氢链霉素倍半硫酸酯, BioReagent, suitable for cell culture, ≥95.0% (HPLC)

product line

BioReagent

Quality Level

200

assay

≥95.0% (HPLC)

form

powder

technique(s)

cell culture | mammalian: suitable

color

white to off-white

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria, mycobacteria

mode of action

protein synthesis | interferes

storage temp.

2-8°C

SMILES string

OS(O)(=O)=O.OS(O)(=O)=O.OS(O)(=O)=O.CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]2[C@@H](O[C@@H](C)[C@]2(O)CO)O[C@@H]3[C@@H](O)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]3NC(N)=N.CN[C@H]4[C@H](O)[C@@H](O)[C@H](CO)O[C@H]4O[C@H]5[C@@H](O[C@@H](C)[C@]5(O)CO)O[C@@H]6[C@@H](O)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]6NC(N)=N

InChI

1S/2C21H41N7O12.3H2O4S/c2*1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;3*1-5(2,3)4/h2*5-18,26,29-36H,3-4H2,1-2H3,(H4,22,23,27)(H4,24,25,28);3*(H2,1,2,3,4)/t2*5-,6-,7-,8+,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,21+;;;/m00.../s1

InChI key

CZWJCQXZZJHHRH-YZTFXSNBSA-N

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General description

Chemical structure: aminoglycoside

Application

Dihydrostreptomycin sesquisulfate is a derivative of streptomycin used in aminoglyside uptake studies. Other studies have also used it as an electrode for a cochlear amplifier in the hair-cell bundle of lizards.

Biochem/physiol Actions

Mode of Action: Dihydrostreptomycin sesquisulfate inhibits protein synthesis at the level o the 30S ribosomal subunit and the 16s rRNA.

pictograms

GHS08,GHS07

signalword

Warning

hcodes

H302,H361fd

pcodes

P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405

Hazard Classifications

Acute Tox. 4 Oral - Repr. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

新产品

此项目有

历史批次信息供参考:

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Quantitative determination of dihydrostreptomycin in bovine tissues and milk by liquid chromatography-electrospray ionization-tandem mass spectrometry.

Marc Cherlet et al.

Journal of mass spectrometry : JMS, 42(5), 647-656 (2007-04-19)

Dihydrostreptomycin (DHS) is an aminoglycoside antibiotic used in veterinary medicine in combination with benzylpenicillin for the treatment of bacterial infections in cattle, pigs and sheep. A method to determine its residues in edible tissues of cattle, as well as in

Clinical and bacteriological response to treatment of clinical mastitis with one of three intramammary antibiotics.

S McDougall et al.

New Zealand veterinary journal, 55(4), 161-170 (2007-08-07)

To compare the proportions of clinical and bacteriological cure of glands of dairy cows diagnosed with clinical mastitis, following treatment with one of three different intramammary antibiotic preparations. Cows from dairy cow herds (n=28) across New Zealand which were diagnosed

Clinical mastitis in Norwegian herds after a combined selective dry-cow therapy and teat-dipping trial.

A C Whist et al.

Journal of dairy science, 89(12), 4649-4659 (2006-11-16)

The objective of this study was to see if introduction of a 2-yr combined selective dry-cow therapy and teat-dipping trial would reduce clinical mastitis (CM) events in 164 Norwegian dairy herds. Three different penicillin or penicillin/dihydrostreptomycin-based dry-cow treatments, and 3

Prevalence and antimicrobial susceptibility of Salmonella in Japanese broiler flocks.

Y Sasaki et al.

Epidemiology and infection, 140(11), 2074-2081 (2012-01-28)

This study determined the prevalence and antimicrobial susceptibility of Salmonella isolated from broiler flocks in Japan. Caecal dropping samples were collected from 288 broiler flocks between November 2007 and February 2010. Salmonella was prevalent in 248 (86·1%) broiler flocks. The

Analysis of impurities in streptomycin and dihydrostreptomycin by hydrophilic interaction chromatography/electrospray ionization quadrupole ion trap/time-of-flight mass spectrometry.

Shin-ichi Kawano

Rapid communications in mass spectrometry : RCM, 23(6), 907-914 (2009-02-19)

Impurities in streptomycin (STR) and dihydrostreptomycin (DHS) were investigated by hydrophilic interaction chromatography/electrospray ionization quadrupole ion trap/time-of-flight mass spectrometry (HILIC/ESI-QIT/TOFMS). Samples were separated on a fused-core silica column (100 mmx2.1 mm i.d., particle size: 2.7 microm) with isocratic elution using

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全球贸易项目编号

货号	GTIN
D5155-100G	04061833586068
D5155-25G	04061833586075

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