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Merck
CN

D5172

十二烷基β-D-麦芽糖苷

BioXtra, ≥98% (GC)

别名:

DDM, 月桂基-β-D-麦芽糖苷

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关于此项目

经验公式(希尔记法):
C24H46O11
化学文摘社编号:
分子量:
510.62
NACRES:
NA.25
PubChem Substance ID:
eCl@ss:
32190102
UNSPSC Code:
12161900
MDL number:
Beilstein/REAXYS Number:
55318
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产品名称

十二烷基β-D-麦芽糖苷, BioXtra, ≥98% (GC)

InChI

1S/C24H46O11/c1-2-3-4-5-6-7-8-9-10-11-12-32-23-21(31)19(29)22(16(14-26)34-23)35-24-20(30)18(28)17(27)15(13-25)33-24/h15-31H,2-14H2,1H3/t15-,16-,17-,18+,19-,20-,21-,22-,23-,24-/m1/s1

SMILES string

CCCCCCCCCCCCO[C@@H]1O[C@H](CO)[C@@H](O[C@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O

InChI key

NLEBIOOXCVAHBD-QKMCSOCLSA-N

description

non-ionic

product line

BioXtra

assay

≥98% (GC)

form

powder

mol wt

micellar avg mol wt 50,000

aggregation number

98

technique(s)

protein purification: suitable
protein quantification: suitable

impurities

≤0.0005% Phosphorus (P)
≤0.1% Insoluble matter

ign. residue

≤0.1%

CMC

0.15 mM (20-25°C)

mp

224-226 °C (lit.)

anion traces

chloride (Cl-): ≤0.05%
sulfate (SO42-): ≤0.05%

cation traces

Al: ≤0.0005%
Ca: ≤0.001%
Cu: ≤0.0005%
Fe: ≤0.0005%
K: ≤0.005%
Mg: ≤0.0005%
NH4+: ≤0.05%
Na: ≤0.05%
Pb: ≤0.001%
Zn: ≤0.0005%

storage temp.

−20°C

Quality Level

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Application

正十二烷基-β-D-麦芽糖苷已被用于评估去污剂对弹性蛋白样多肽(ELP)的热行为的影响。它还被用于研究膜结构如何响应氨基酸序列的去污剂溶解。
非离子型去污剂,用于提取和溶解蛋白质。
非离子型去污剂,用于酶的稳定和活化以及用于膜研究。

General description

正十二烷基-β-D-麦芽糖苷是属于烷基多葡糖苷家族的非离子表面活性剂。

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

涉药品监管产品
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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Rotational Diffusion of Coumarin 153 in Nanoscopic Micellar Environments of n-dodecyl-β-D-maltoside and n-dodecyl-hexaethylene-glycol Mixtures
Hierrezuelo, H. and C. Ruiz
The Journal of Physical Chemistry, 116, 12476-12476 (2012)
Effect of detergents on the thermal behavior of elastin-like polypeptides
Thapa, A.
Biopolymers, 99, 55-55 (2012)
Vincent G Nadeau et al.
Biochemistry, 51(31), 6228-6237 (2012-07-12)
The ability to predict from amino acid sequence how membrane protein structures will respond to detergent solubilization would significantly facilitate experimental characterization of these molecules. Here we have investigated and compared the response to solubilization by the "mild" n-dodecyl-β-D-maltoside (DDM)
Antonello Calcutta et al.
Biochimica et biophysica acta, 1818(9), 2290-2301 (2012-04-25)
Membrane proteins are vital for biological function, and their action is governed by structural properties critically depending on their interactions with the membranes. This has motivated considerable interest in studies of membrane protein folding and unfolding. Here the structural changes
Ka Young Chung et al.
The Journal of biological chemistry, 287(43), 36305-36311 (2012-08-16)
The G protein-coupled β(2)-adrenoreceptor (β(2)AR) signals through the heterotrimeric G proteins G(s) and G(i) and β-arrestin. As such, the energy landscape of β(2)AR-excited state conformers is expected to be complex. Upon tagging Cys-265 of β(2)AR with a trifluoromethyl probe, (19)F

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