质量水平
方案
≥99%
表单
solid
储存温度
−20°C
SMILES字符串
COC1=C(OC)C(=O)c2ccccc2C1=O
InChI
1S/C12H10O4/c1-15-11-9(13)7-5-3-4-6-8(7)10(14)12(11)16-2/h3-6H,1-2H3
InChI key
ZEGDFCCYTFPECB-UHFFFAOYSA-N
相关类别
应用
2,3-二甲氧基-1,4-萘醌已被用于研究乙醇对低氧和高氧条件下足细胞凋亡的影响。
用于研究ROS在细胞毒性、细胞凋亡和坏死中的作用。
生化/生理作用
2,3-二甲氧基-1,4-萘醌（DMNQ）具有通过氧化还原循环产生H2O2的能力，但无法与谷胱甘肽（GSH）结合。
警示用语：
Warning
危险声明
危险分类
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
dust mask type N95 (US), Eyeshields, Gloves
Koji Kawata et al.
Environmental science & technology, 41(10), 3769-3774 (2007-06-06)
Microarray technology is proving to be a useful tool to classify undefined environmental toxicants, to investigate underlying mechanisms of toxicity, and to identify candidate toxicant-specific genetic markers by examining global effects of putative toxicants on gene expression profiles. The aim
Haibin Cui et al.
Journal of anesthesia, 35(3), 394-404 (2021-04-07)
Dexmedetomidine (DEX) has been associated with inflammation, oxidative stress, and apoptosis, but its effects on lipopolysaccharide (LPS)-induced lung injury remain uncertain. The present study explored the effects of DEX on LPS-induced lung injury and studied the possible molecular mechanisms by
R Bose et al.
Cell death & disease, 1, e92-e92 (2010-01-01)
Alterations in intrauterine programming occurring during critical periods of development have adverse consequences for whole-organ systems or individual tissue functions in later life. In this paper, we show that rat embryonic neural stem cells (NSCs) exposed to the synthetic glucocorticoid
Extracellular glutathione and gamma-glutamyl transpeptidase prevent H2O2-induced injury by 2, 3-dimethoxy-1, 4-naphthoquinone
Shi M, et al.
Free radical biology & medicine, 15(1), 57-67 (1993)
J M Dypbukt et al.
The Journal of biological chemistry, 269(48), 30553-30560 (1994-12-02)
Increasing concentrations (1-100 microM) of the redox cycling quinone, 2,3-dimethoxy-1,4-naphthoquinone (DMNQ), stimulated growth, triggered apoptosis, or caused necrosis of pancreatic RINm5F cells, depending on the dose and duration of the exposure. Following the exposure of RINm5F cells to 10 microM
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