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Merck
CN

D5520

二烷酸二甲酯

for histidine methylation

别名:

DMPC, Dimethyl pyrocarbonate, Pyrocarbonic acid dimethyl ester

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关于此项目

线性分子式:
(CH3OCO)2O
化学文摘社编号:
分子量:
134.09
EC Number:
224-859-8
UNSPSC Code:
12352202
PubChem Substance ID:
Beilstein/REAXYS Number:
956715
MDL number:
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InChI key

GZDFHIJNHHMENY-UHFFFAOYSA-N

InChI

1S/C4H6O5/c1-7-3(5)9-4(6)8-2/h1-2H3

SMILES string

COC(=O)OC(=O)OC

biological source

synthetic

form

liquid

refractive index

n20/D 1.392 (lit.)

bp

45-46 °C/5 mmHg (lit.)

density

1.25 g/mL at 25 °C (lit.)

storage temp.

room temp

Application

Methylates one or two histidine residues at the active site of PEP carboxykinase; the resulting inhibition is only partially reversible.

pictograms

Skull and crossbonesCorrosion

signalword

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - Skin Corr. 1B

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

185.0 °F

flash_point_c

85 °C

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter

法规信息

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分析证书(COA)

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J Peters et al.
Scientific reports, 7(1), 15339-15339 (2017-11-12)
We compared the effect of cholesterol at different concentration on the phase behaviour of DMPC (1,2-dimyristoyl-sn-glycero-3-phosphocholine) multilamellar vesicles. We used pressure perturbation differential scanning calorimetry (PPC) that studies a system on the whole by giving access to relevant thermodynamic quantities
Arne Raasakka et al.
Scientific reports, 9(1), 642-642 (2019-01-27)
Compact myelin forms the basis of nerve insulation essential for higher vertebrates. Dozens of myelin membrane bilayers undergo tight stacking, and in the peripheral nervous system, this is partially enabled by myelin protein zero (P0). Consisting of an immunoglobulin (Ig)-like
Hirohide Takahashi et al.
Small (Weinheim an der Bergstrasse, Germany), 12(44), 6106-6113 (2016-09-21)
With nanometer lateral and Angstrom vertical resolution, atomic force microscopy (AFM) has contributed unique data improving the understanding of lipid bilayers. Lipid bilayers are found in several different temperature-dependent states, termed phases; the main phases are solid and fluid phases.
Makiko Nakata et al.
Langmuir : the ACS journal of surfaces and colloids, 35(31), 10007-10013 (2019-01-15)
Microbubbles have potential for applications as drug and gene delivery systems, in which the release of a substance is triggered by an ultrasonic pulse. In this paper, we discuss the adsorption and desorption of a film of phospholipid on the
Astrid Peschel et al.
The Journal of chemical physics, 145(20), 204904-204904 (2016-12-03)
Quartz crystal microbalance (QCM) is emerging as a versatile tool for studying lipid phase behavior. The technique is attractive for fundamental biophysical studies as well applications because of its simplicity, flexibility, and ability to work with very small amounts of

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