D6277
N-Decanoyl-N-methylglucamine
≥98% (GC)
别名:
N-(D-Glucityl)-N-methyldecanamide, N-Decanoyl-N-methyl-D-glucamine, MEGA-10
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关于此项目
经验公式（希尔记法）:
C17H35NO6
化学文摘社编号:
分子量:
349.46
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6974359
产品名称
N-Decanoyl-N-methylglucamine, ≥98% (GC)
InChI
1S/C17H35NO6/c1-3-4-5-6-7-8-9-10-15(22)18(2)11-13(20)16(23)17(24)14(21)12-19/h13-14,16-17,19-21,23-24H,3-12H2,1-2H3
SMILES string
OCC(O)C(O)C(O)C(O)CN(C)C(CCCCCCCCC)=O
InChI key
UMWKZHPREXJQGR-UHFFFAOYSA-N
description
non-ionic
assay
≥98% (GC)
form
powder
mol wt
349.46 g/mol
technique(s)
ligand binding assay: suitable
protein purification: suitable
CMC
6-7 mM (20-25°C)
storage temp.
2-8°C
Quality Level
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Application
N-Decanoyl-N-methylglucamine has been used in a study to assess the effect of surfactants on wetting behavior of super-hydrophobic surfaces. It has also been used in a study to investigate the clinical impact of Human metapneumovirus (hMPV) vaccines on Syrian golden hamsters.
Non-ionic, dialyzable detergent used for the solubilization of membrane proteins
General description
N-Decanoyl-N-methylglucamine is a nonionic detergent used in lysis buffers.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Sander Herfst et al.
The Journal of general virology, 88(Pt 10), 2702-2709 (2007-09-18)
Human metapneumovirus (hMPV), a newly discovered paramyxovirus, is associated with acute respiratory-tract illness, primarily in young children, individuals with underlying disease and the elderly. Two genetic lineages of hMPV circulate around the world, and viruses from these two lineages demonstrate
Khemraj Budachetri et al.
mBio, 11(4) (2020-07-30)
Ehrlichia chaffeensis is an obligatory intracellular bacterium that causes human monocytic ehrlichiosis, an emerging disease transmitted by the Lone Star tick, Amblyomma americanum. E. chaffeensis outer membrane protein entry triggering protein of Ehrlichia (EtpE) is necessary for bacterial entry into
R C Poole et al.
The Biochemical journal, 283 ( Pt 3), 855-862 (1992-05-01)
1. Intact erythrocytes were incubated with 100 microM-4,4'-di-isothiocyanostilbene-2,2'-disulphonate (DIDS), a concentration sufficient to inhibit lactate transport irreversibly by 65%. DIDS-labelled proteins were detected by immunoblotting of erythrocyte membrane proteins with an anti-DIDS antibody. Labelled polypeptides of 35-45 kDa in rat
C Carnero Ruiz et al.
Biomacromolecules, 8(8), 2497-2503 (2007-07-17)
The protein-surfactant system constituted by bovine serum albumin (BSA) and N-decanoyl-N-methylglucamide (MEGA-10) has been studied by using surface tension, steady-state fluorescence, and dynamic light scattering measurements. It was found that the presence of protein delays the surfactant aggregation, which was
T Wakagi et al.
Biochemical and biophysical research communications, 165(3), 1110-1114 (1989-12-29)
Cytochrome C oxidase was solubilized with a nonionic detergent n-decanoyl-N-methyl glucamide from the membranes of Sulfolobus acidocaldarius, a thermoacidophilic archaebacterium, and was purified. The enzyme oxidized horse heart cytochrome C with a Vmax of 63 mumols/min/mg at 50 degrees C.
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