D6277
N-Decanoyl-N-methylglucamine
≥98% (GC)
别名:
N-(D-Glucityl)-N-methyldecanamide, N-Decanoyl-N-methyl-D-glucamine, MEGA-10
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关于此项目
经验公式（希尔记法）:
C17H35NO6
化学文摘社编号:
分子量:
349.46
UNSPSC Code:
12161900
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
6974359
InChI
1S/C17H35NO6/c1-3-4-5-6-7-8-9-10-15(22)18(2)11-13(20)16(23)17(24)14(21)12-19/h13-14,16-17,19-21,23-24H,3-12H2,1-2H3
SMILES string
OCC(O)C(O)C(O)C(O)CN(C)C(CCCCCCCCC)=O
InChI key
UMWKZHPREXJQGR-UHFFFAOYSA-N
description
non-ionic
assay
≥98% (GC)
form
powder
mol wt
349.46 g/mol
technique(s)
ligand binding assay: suitable, protein purification: suitable
CMC
6-7 mM (20-25°C)
storage temp.
2-8°C
Quality Level
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General description
N-Decanoyl-N-methylglucamine is a nonionic detergent used in lysis buffers.
Application
N-Decanoyl-N-methylglucamine has been used in a study to assess the effect of surfactants on wetting behavior of super-hydrophobic surfaces. It has also been used in a study to investigate the clinical impact of Human metapneumovirus (hMPV) vaccines on Syrian golden hamsters.
Non-ionic, dialyzable detergent used for the solubilization of membrane proteins
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Khemraj Budachetri et al.
mBio, 11(4) (2020-07-30)
Ehrlichia chaffeensis is an obligatory intracellular bacterium that causes human monocytic ehrlichiosis, an emerging disease transmitted by the Lone Star tick, Amblyomma americanum. E. chaffeensis outer membrane protein entry triggering protein of Ehrlichia (EtpE) is necessary for bacterial entry into
Sander Herfst et al.
The Journal of general virology, 88(Pt 10), 2702-2709 (2007-09-18)
Human metapneumovirus (hMPV), a newly discovered paramyxovirus, is associated with acute respiratory-tract illness, primarily in young children, individuals with underlying disease and the elderly. Two genetic lineages of hMPV circulate around the world, and viruses from these two lineages demonstrate
Optimal concentrations of N-decanoyl-N-methylglucamine and sodium dodecyl sulfate allow the extraction and analysis of membrane proteins
Chuang, J., et al.
Analytical Biochemistry, 418, 3-3 (2011)
R Mohammadi et al.
Langmuir : the ACS journal of surfaces and colloids, 20(22), 9657-9662 (2004-10-20)
The effect of surfactants on wetting behavior of super-hydrophobic surfaces was investigated. Super-hydrophobic surfaces were prepared of alkylketene dimer (AKD) by casting the AKD melt in a specially designed mold. Time-dependent studies were carried out, using the axisymmetric drop shape
R C Poole et al.
The Biochemical journal, 283 ( Pt 3), 855-862 (1992-05-01)
1. Intact erythrocytes were incubated with 100 microM-4,4'-di-isothiocyanostilbene-2,2'-disulphonate (DIDS), a concentration sufficient to inhibit lactate transport irreversibly by 65%. DIDS-labelled proteins were detected by immunoblotting of erythrocyte membrane proteins with an anti-DIDS antibody. Labelled polypeptides of 35-45 kDa in rat
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