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关于此项目
经验公式(希尔记法):
C16H16N2O2
化学文摘社编号:
分子量:
268.31
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
产品名称
DMeOB, ≥98% (HPLC), solid
InChI key
FBNPHFBYHYNMHC-JYFOCSDGSA-N
SMILES string
COc1cccc(\C=N\N=C\c2cccc(OC)c2)c1
InChI
1S/C16H16N2O2/c1-19-15-7-3-5-13(9-15)11-17-18-12-14-6-4-8-16(10-14)20-2/h3-12H,1-2H3/b17-11+,18-12+
assay
≥98% (HPLC)
form
solid
color
yellow
solubility
DMSO: ~28 mg/mL
H2O: insoluble
storage temp.
2-8°C
Quality Level
Biochem/physiol Actions
Negative allosteric modulator at the metabotropic glutamate receptor mGluR5.
Features and Benefits
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
signalword
Danger
hcodes
Hazard Classifications
Aquatic Acute 1 - Eye Dam. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
法规信息
新产品
此项目有
A family of highly selective allosteric modulators of the metabotropic glutamate receptor subtype 5.
Julie A O'Brien et al.
Molecular pharmacology, 64(3), 731-740 (2003-08-16)
We have identified a family of highly selective allosteric modulators of the group I metabotropic glutamate receptor subtype 5 (mGluR5). This family of closely related analogs exerts a spectrum of effects, ranging from positive to negative allosteric modulation, and includes
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