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Merck
CN

D6898

脱氧核糖核酸 钠盐 来源于鲱鱼睾丸

Type XIV

别名:

DNA

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关于此项目

化学文摘社编号:
UNSPSC Code:
41106305
eCl@ss:
32160414
NACRES:
NA.51
MDL number:
Form:
solid
Solubility:
water: 2 mg/mL, clear to hazy, colorless
Storage temp.:
2-8°C
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type

Type XIV

Quality Level

form

solid

color

white

solubility

water: 2 mg/mL, clear to hazy, colorless

storage temp.

2-8°C

General description

来自鲱鱼睾丸的脱氧核糖核酸钠盐,也称为HtDNA,是DNA结合剂研究的天然DNA来源。 HtDNA的检出限约为5.0ng,光散射强度(I(LS))的线性范围为0.05 ~ 2.5 mµg。

Application

从鲱鱼睾丸中提取的脱氧核糖核酸钠盐被用于研究调节DNA结构和功能的DNA结合剂。鲱鱼睾丸DNA也用于溶液中DNA行为的物理化学研究。

存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

法规信息

低风险生物材料

此项目有


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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X Du et al.
Talanta, 55(1), 93-98 (2008-10-31)
The interaction of histone with nucleic acids was characterized by light-scattering measurement using a common spectrofluorometer. Thereby, a sensitive and convenient method for the determination of nucleic acids was established. At pH 4.5-6.5, the interaction of histone with nucleic acids
Larisa I Labzin et al.
The EMBO journal, 38(21), e101365-e101365 (2019-08-31)
Inflammasomes are potent innate immune signalling complexes that couple cytokine release with pro-inflammatory cell death. However, pathogens have evolved strategies to evade this cell autonomous system. Here, we show how antibodies combine with innate sensors in primary human macrophages to
Assaf Marcus et al.
Immunity, 49(4), 754-763 (2018-10-18)
Detection of cytosolic DNA by the enzyme cGAS triggers the production of cGAMP, a second messenger that binds and activates the adaptor protein STING, which leads to interferon (IFN) production. Here, we found that in vivo natural killer (NK) cell killing
Gillian Dunphy et al.
Molecular cell, 71(5), 745-760 (2018-09-08)
DNA damage can be sensed as a danger-associated molecular pattern by the innate immune system. Here we find that keratinocytes and other human cells mount an innate immune response within hours of etoposide-induced DNA damage, which involves the DNA sensing
Katherine R Balka et al.
Cell reports, 31(1), 107492-107492 (2020-04-09)
Stimulator of Interferon Genes (STING) is a critical component of host innate immune defense but can contribute to chronic autoimmune or autoinflammatory disease. Once activated, the cyclic guanosine monophosphate (GMP)-adenosine monophosphate (AMP) (cGAMP) synthase (cGAS)-STING pathway induces both type I interferon

全球贸易项目编号

货号GTIN
D6898-1G04061826761694
D6898-250MG04061833587966
D6898-10G04061833587959

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