D7409
2′,3′-双脱氧鸟苷 5′-三磷酸 钠盐
≥90% (HPLC)
别名:
ddGTP
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关于此项目
经验公式（希尔记法）:
C10H16N5O12P3
化学文摘社编号:
分子量:
491.18
MDL编号:
UNSPSC代码:
41106305
PubChem化学物质编号:
NACRES:
NA.51
方案
≥90% (HPLC)
表单
powder
溶解性
water: 5 mg/mL, clear, colorless
储存温度
−20°C
SMILES字符串
[Na+].OP([O-])(=O)OP(O)(=O)OP(O)(=O)OC[C@@H]1CC[C@@H](O1)n2cnc3C(=O)NC(=N)Nc23
InChI
1S/C10H16N5O12P3.Na/c11-10-13-8-7(9(16)14-10)12-4-15(8)6-2-1-5(25-6)3-24-29(20,21)27-30(22,23)26-28(17,18)19;/h4-6H,1-3H2,(H,20,21)(H,22,23)(H2,17,18,19)(H3,11,13,14,16);/q;+1/p-1/t5-,6+;/m0./s1
InChI key
XCOBCPBPAINELA-RIHPBJNCSA-M
基因信息
human ... HRAS(3265)
应用
2′,3′-二脱氧鸟苷 5′-三磷酸（ddGTP） 用作链终止剂抑制剂和端粒酶抑制剂。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type N95 (US)
C Strahl et al.
Nucleic acids research, 22(6), 893-900 (1994-03-25)
The ribonucleoprotein enzyme telomerase is a specialized type of cellular reverse transcriptase which synthesizes one strand of telomeric DNA, using as the template a sequence in the RNA moiety of telomerase. We analyzed the effects of various nucleoside analogs, known
A Y Howe et al.
Hepatology (Baltimore, Md.), 23(1), 87-96 (1996-01-01)
Hepatitis B virus (HBV) replication is mediated by the viral polymerase that possesses three functional domains: primer, DNA polymerase/reverse transcriptase, and RNase H. Using the Pekin duck as an animal model, we demonstrate a novel mechanism of inhibition of duck
Joeri Auwerx et al.
Molecular pharmacology, 61(2), 400-406 (2002-01-26)
Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are specific for human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) and do not inhibit HIV-2. Given that the amino acids lining the NNRTI-specific pocket of HIV-1 RT display higher similarity to the corresponding
Y Li et al.
Proceedings of the National Academy of Sciences of the United States of America, 96(17), 9491-9496 (1999-08-18)
The Taq DNA polymerase is the most commonly used enzyme in DNA sequencing. However, all versions of Taq polymerase are deficient in two respects: (i) these enzymes incorporate each of the four dideoxynucleoside 5' triphosphates (ddNTPs) at widely different rates
A Bart et al.
Nucleic acids research, 33(14), e124-e124 (2005-08-11)
The identification of methylated sites on bacterial genomic DNA would be a useful tool to study the major roles of DNA methylation in prokaryotes: distinction of self and nonself DNA, direction of post-replicative mismatch repair, control of DNA replication and
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