D7571
Dimaprit dihydrochloride
≥98% (NMR)
别名:
Carbamimidothioic acid, 3-(dimethylamino)propyl ester, hydrochloride (1:2), Dimaprit-2HCl
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关于此项目
经验公式（希尔记法）:
C6H15N3S · 2HCl
化学文摘社编号:
分子量:
234.19
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (NMR)
Form:
powder
Quality Segment
assay
≥98% (NMR)
form
powder
color
white to off-white
solubility
H2O: ≥50 mg/mL
originator
Roche
storage temp.
−20°C
SMILES string
Cl.Cl.CN(C)CCCSC(N)=N
InChI
1S/C6H15N3S.2ClH/c1-9(2)4-3-5-10-6(7)8;;/h3-5H2,1-2H3,(H3,7,8);2*1H
InChI key
DFWCPLGXFMSUCW-UHFFFAOYSA-N
Biochem/physiol Actions
Selective histamine receptor H2 agonist.
The histamine H2 receptor influences various cardiovascular responses, including vasodilation and cardiac rhythm, regulates gastric acid secretion, and also plays a role in the immune system by inhibiting antibody production, T cell proliferation and cytokine production. Histamine receptors are members of the GPCR family, and H2 mediates cell signaling via internalization and interaction with the GTPase dynamin.
Features and Benefits
This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
警示词
Warning
危险代码
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
靶器官
Respiratory system
存储类别
11 - Combustible Solids
怎么回事？
WGK 3
闪点 (F)
Not applicable
闪点 (°C)
Not applicable