产品名称
磷酸二乙基伞形酮, ≥98% (HPLC), oil
SMILES string
CCOP(=O)(OCC)Oc1ccc2C(C)=CC(=O)Oc2c1
InChI
1S/C14H17O6P/c1-4-17-21(16,18-5-2)20-11-6-7-12-10(3)8-14(15)19-13(12)9-11/h6-9H,4-5H2,1-3H3
InChI key
GHGRYKAFUNNHBG-UHFFFAOYSA-N
assay
≥98% (HPLC)
form
oil
color
colorless to yellow
solubility
DMSO: >5 mg/mL
storage temp.
−20°C
Quality Level
Application
磷酸二乙酯已被用作脂肪酶抑制剂来治疗野生型成髓细胞，以进行体外中性粒细胞分化试验。
Biochem/physiol Actions
二乙基伞形磷酸酯（DEUP）是一种在体外不阻断蛋白激酶活性A的有机磷酸酯。
二乙基伞形酮磷酸酯是一种选择性的、有效的胆固醇酯酶抑制剂。它主要通过防止胆固醇转运到类固醇生成细胞的线粒体中来阻止类固醇生成。预期胆固醇酯酶抑制剂会限制饮食中胆固醇的吸收。IC50 = 11.6 μM。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
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We explored the relations between indices of mechanical stability of vertical posture and synergy indices under unexpected perturbations. The main hypotheses predicted higher posture-stabilizing synergy indices and higher mechanical indices of center of pressure stability during perturbations perceived by subjects
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Resting state connectivity aims to identify spontaneous cerebral hemodynamic fluctuations that reflect neuronal activity at rest. In this study, we investigated the spatial-temporal correlation of hemoglobin concentration signals over the whole head during the resting state. By choosing a source-detector
Y S Choi et al.
European journal of biochemistry, 234(2), 680-685 (1995-12-01)
Diethylumbelliferyl phosphate (DEUP) is an organophosphate cholesteryl ester hydrolase inhibitor that blocks steroidogenesis mainly by preventing cholesterol transport into the mitochondria of steroidogenic cells. In the present study, we show that DEUP blocks the cAMP-stimulated mitochondrial accumulation of the 30-kDa
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American journal of physiology. Renal physiology, 313(5), F1089-F1096 (2017-08-05)
Multiple vaginal parities have been reported to be an important risk factor for stress urinary incontinence (SUI). Simulated birth trauma with single vaginal distention (VD) has been used to induce the SUI condition in animals; however, the effect of multiple
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In 2011, the California Right Care Initiative implemented a countywide physician organization learning collaborative called University of Best Practices (UBP) in San Diego County for major healthcare systems and physician organizations to share best practices in managing cardiovascular and cerebrovascular
商品
Cholesterol esterification enhances transport efficiency in lipoproteins for increased blood stream transport.
胆固醇酯化可改善运输。胆固醇酯可更轻松地封装在脂蛋白内部-增加了在血液中可轻松运输的胆固醇数量。
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