产品名称
磷酸二乙基伞形酮, ≥98% (HPLC), oil
Quality Level
assay
≥98% (HPLC)
form
oil
color
colorless to yellow
solubility
DMSO: >5 mg/mL
storage temp.
−20°C
SMILES string
CCOP(=O)(OCC)Oc1ccc2C(C)=CC(=O)Oc2c1
InChI
1S/C14H17O6P/c1-4-17-21(16,18-5-2)20-11-6-7-12-10(3)8-14(15)19-13(12)9-11/h6-9H,4-5H2,1-3H3
InChI key
GHGRYKAFUNNHBG-UHFFFAOYSA-N
Application
磷酸二乙酯已被用作脂肪酶抑制剂来治疗野生型成髓细胞，以进行体外中性粒细胞分化试验。
Biochem/physiol Actions
二乙基伞形酮磷酸酯是一种选择性的、有效的胆固醇酯酶抑制剂。它主要通过防止胆固醇转运到类固醇生成细胞的线粒体中来阻止类固醇生成。预期胆固醇酯酶抑制剂会限制饮食中胆固醇的吸收。IC50 = 11.6 μM。
二乙基伞形磷酸酯（DEUP）是一种在体外不阻断蛋白激酶活性A的有机磷酸酯。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
J G Delamatre et al.
Journal of cellular physiology, 157(1), 164-168 (1993-10-01)
Diethylumbelliferyl phosphate (UBP) has been shown to inhibit the neutral cholesteryl ester hydrolase activity responsible for hydrolysis of cellular lipid droplet cholesteryl ester (Harrison et al., 1990). The potential for (UBP) to inhibit uptake and hydrolysis of high density lipoprotein
P M Gocze et al.
Cytometry, 17(2), 151-158 (1994-10-01)
Neutral lipids accumulate in cellular lipid droplets. These droplets vary remarkably in number and amount between cells. In the present studies, the variability in lipid content was quantified by comparing the coefficient of variation of fluorescence histograms of nile red
Stephen A Brose et al.
Rapid communications in mass spectrometry : RCM, 26(20), 2472-2476 (2012-09-15)
Fatty acids (FA) labeled with (18) O at the carboxyl group, including oxidized species (FA(18) O), are a useful, low-cost, and easy to prepare tool for quantitative and qualitative mass spectrometry (MS) analysis in biological systems. In addition, they are
Daniel P Heil et al.
Journal of the International Society of Sports Nutrition, 9, 8-8 (2012-03-22)
Previous research has shown that ingestion of substances that enhance the body's hydrogen ion buffering capacity during high intensity exercise can improve exercise performance. The present study aimed to determine whether the chronic ingestion of an alkalizing supplement, which purports
Jason M Meyer et al.
Journal of lipid research, 53(10), 2081-2091 (2012-07-27)
Macrophage foam cells are a defining pathologic feature of atherosclerotic lesions. Recent studies have demonstrated that at high concentrations associated with hypercholesterolemia, native LDL induces macrophage lipid accumulation. LDL particles are taken up by macrophages as part of bulk fluid
商品
Cholesterol esterification enhances transport efficiency in lipoproteins for increased blood stream transport.
胆固醇酯化可改善运输。胆固醇酯可更轻松地封装在脂蛋白内部-增加了在血液中可轻松运输的胆固醇数量。
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| D7692-5MG | 04061833588758 |
| D7692-25MG | 04061833057506 |
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持