Merck
CN
所有图片(3)

文件

D7910

Sigma-Aldrich

3,4-二氯异香豆素

serine protease inhibitor

登录查看公司和协议定价
所有图片(3)
别名:
3,4-DCI, 3,4-二氯-2-苯并吡喃-1-酮
经验公式（希尔记法）:
C9H4Cl2O2
CAS号:
51050-59-0
分子量:
215.03
Beilstein:
6802625
MDL编号:
MFCD00036960
PubChem化学物质编号:
24278386
NACRES:
NA.77

质量水平

200

检测方案

≥98% (TLC)

形式

powder

溶解性

ethyl acetate: 49.00-51.00 mg/mL, clear, colorless to faintly yellow

储存温度

2-8°C

SMILES字符串

ClC1=C(Cl)c2ccccc2C(=O)O1

InChI

1S/C9H4Cl2O2/c10-7-5-3-1-2-4-6(5)9(12)13-8(7)11/h1-4H

InChI key

SUGXUUGGLDCZKB-UHFFFAOYSA-N

正在寻找类似产品? Visit 产品对比指南

应用

可用于巨噬细胞的快速染色鉴定；通过更复杂的形态学标准、吞噬作用和 Fc 受体的存在证实了该方法的计数。

其他说明

有效浓度为 5-100μM。

数量

PH 7.5 时半衰期 = 20 分钟。

底物

丝氨酸蛋白酶抑制剂。对包括颗粒酶内部的多种丝氨酸蛋白酶具有活性。对β-内酰胺酶无活性。

象形图

Skull and crossbones
GHS06

警示用语：

Danger

危险分类

Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

靶器官

Respiratory system

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

为方便起见，与您过往购买产品相关的文件已保存在文档库中。

访问文档库

难以找到您所需的产品或批次号码？

在网站页面上，产品编号会附带包装尺寸/数量一起显示（例如：T1503-25G）。请确保 在“产品编号”字段中仅输入产品编号 (示例: T1503).

示例

T1503
货号
-
25G
包装规格/数量

其它示例：

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

输入内容 1.000309185)

遇到问题？欢迎随时联系我们技术服务 寻求帮助

批号可以在产品标签上"批“ （Lot或Batch）字后面找到。

Aldrich 产品

  • 如果您查询到的批号为 TO09019TO 等，请输入去除前两位字母的批号：09019TO。

  • 如果您查询到的批号含有填充代码（例如05427ES-021），请输入去除填充代码-021的批号：05427ES。

  • 如果您查询到的批号含有填充代码（例如 STBB0728K9），请输入去除填充代码K9的批号：STBB0728。

未找到您寻找的产品？

部分情况下，可能未在线提供COA。如果搜索不到COA，可在线索取。

索取COA

A Weihofen et al.
The Journal of biological chemistry, 275(40), 30951-30956 (2000-08-02)
Signal peptides of secretory and membrane proteins are generated by proteolytic processing of precursor proteins after insertion into the endoplasmic reticulum membrane. Liberated signal peptides can be further processed, and the resulting N-terminal fragments are released toward the cytosol, where
V Conseil et al.
Antimicrobial agents and chemotherapy, 43(6), 1358-1361 (1999-05-29)
We investigated the effect of protease inhibitors on the asexual development of the protozoan parasite Toxoplasma gondii. Among the inhibitors tested only two irreversible serine protease inhibitors, 3,4-dichloroisocoumarin and 4-(2-aminoethyl)-benzenesulfonyl fluoride, clearly prevented invasion of the host cells by specifically
Diego López León et al.
iScience, 23(3), 100932-100932 (2020-03-11)
Pathogenic bacteria secrete virulence factors that interact with the human host to establish infections. The human immune system evolved multiple mechanisms to fight bacterial invaders, including immune proteases that were demonstrated to contribute crucially to antibacterial defense. Here we show
Premkumari Kumarathasan et al.
Particle and fibre toxicology, 15(1), 34-34 (2018-08-12)
There is a paucity of mechanistic information that is central to the understanding of the adverse health effects of source emission exposures. To identify source emission-related effects, blood and saliva samples from healthy volunteers who spent five days near a
Brett M Babin et al.
Cell chemical biology, 29(5), 897-909 (2021-10-03)
The increasing incidence of antibiotic-resistant Mycobacterium tuberculosis infections is a global health threat necessitating the development of new antibiotics. Serine hydrolases (SHs) are a promising class of targets because of their importance for the synthesis of the mycobacterial cell envelope.
查看所有相关文献

商品

Elastase

Enzyme Explorer Product Application Index for Elastase. Leukocyte elastase is a 29KDa serine endoprotease of the Proteinase S1 Family. It exists as a single 238 amino acid-peptide chain with four disulfide bonds.

半胱氨酸蛋白酶——木瓜蛋白酶的特性和产品

木瓜蛋白酶是肽酶C1家族的一种半胱氨酸蛋白酶。它由单一多肽链组成，含有三个二硫键和一个酶活性所必需的巯基。

Papain, Cysteine Protease, Properties & Products

Uncover properties and applications of the cysteine protease papain and find inhibitors, substrates, and other papain products.

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系技术服务部门