D8040
反式 -U-50488 甲磺酸盐
别名:
反 -(±)-3,4-二氯-N-甲基-N- [2-（1-吡咯烷基）环己基] 苯乙酰胺 甲磺酸盐, U-50488H
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选择尺寸
关于此项目
经验公式（希尔记法）:
C19H26Cl2N2O · CH4O3S
分子量:
465.43
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:
Form:
powder
Quality level:
InChI
1S/C19H26Cl2N2O.CH4O3S/c1-22(19(24)13-14-8-9-15(20)16(21)12-14)17-6-2-3-7-18(17)23-10-4-5-11-23;1-5(2,3)4/h8-9,12,17-18H,2-7,10-11,13H2,1H3;1H3,(H,2,3,4)/t17-,18-;/m1./s1
SMILES string
CS(O)(=O)=O.CN([C@@H]1CCCC[C@H]1N2CCCC2)C(=O)Cc3ccc(Cl)c(Cl)c3
InChI key
OJPHNZCUXUUVKU-JAXOOIEVSA-N
form
powder
solubility
H2O: 50 mg/mL
storage temp.
2-8°C
Quality Level
Gene Information
human ... OPRK1(4986)
Application
(±)-反式-U-50488 甲磺酸盐已被用作 κ -阿片受体的对照激动剂。
Biochem/physiol Actions
选择性 κ-已知阿片受体激动剂 (±)-反式-U-50488 甲磺酸盐可诱导利尿。研究发现 U-50488H 与其联合给药时可预防吗啡耐受。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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