D8399
达那唑
≥98%
别名:
17β-羟基-2,4,17α-妊娠双烯-20-炔并[2,3-d]异恶唑, 2,4,17α-妊娠双烯-20-炔并[2,3-d]异恶唑-17-醇
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关于此项目
经验公式（希尔记法）:
C22H27NO2
化学文摘社编号:
分子量:
337.46
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
EC Number:
241-270-1
MDL number:
Quality Level
assay
≥98%
form
powder
drug control
regulated under CDSA - not available from Sigma-Aldrich Canada
SMILES string
CC12Cc3cnoc3C=C1CCC4C2CCC5(C)C4CC[C@@]5(O)C#C
InChI
1S/C22H27NO2/c1-4-22(24)10-8-18-16-6-5-15-11-19-14(13-23-25-19)12-20(15,2)17(16)7-9-21(18,22)3/h1,11,13,16-18,24H,5-10,12H2,2-3H3/t16?,17?,18?,20?,21?,22-/m0/s1
InChI key
POZRVZJJTULAOH-ZIKCMSSPSA-N
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相关类别
Biochem/physiol Actions
达那唑是一种弱的雄性激素；垂体前叶抑制剂。
Features and Benefits
该化合物是由 Sanofi Aventis开发。如需浏览其他药物开发的化合物和批准的药物/候选药物清单，请单击此处。
Packaging
无底玻璃瓶。内含物装在锥底内插管中。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
兴奋剂蛋白同化制剂
此项目有
Timothy J Craig
Allergy and asthma proceedings, 29(3), 225-231 (2008-04-05)
Hereditary angioedema (HAE) is an autosomal dominant disease characterized by painful, recurrent attacks of inflammation affecting the hands, feet, face, abdomen, urogenital tract, and the larynx. The inflammation can be disfiguring, debilitating, quite painful, and, in the case of laryngeal
Pagalavan Letchumanan et al.
Seminars in arthritis and rheumatism, 40(4), 298-306 (2010-06-15)
To review and summarize published information on the use, effectiveness, and adverse effects of danazol in patients with systemic lupus erythematosus (SLE). A MEDLINE search from January 1950 to July 2009 was conducted using 2 search strategies retrieving 51 and
H Farkas et al.
Allergy, 67(12), 1586-1593 (2012-10-03)
Hereditary angioedema is a potentially life-threatening disorder, because edema occurring in the mucosa of the upper airways can lead to suffocation. The management of HAE consists of avoiding the triggering factors, prophylaxis, and the acute treatment of edematous episodes. Medical
E Hughes et al.
The Cochrane database of systematic reviews, (1)(1), CD000069-CD000069 (2007-01-27)
The synthetic androgen Danazol, was developed in the 1970's as a treatment for endometriosis. Its use was soon advocated in women with unexplained subfertility. Two randomised trials were subsequently conducted to assess the effectiveness of danazol in this population. The
V Selak et al.
The Cochrane database of systematic reviews, (4)(4), CD000068-CD000068 (2007-10-19)
Endometriosis is defined as the presence of endometrial tissue (stromal and glandular) outside the normal uterine cavity. Conventional medical and surgical treatments for endometriosis aim to remove or decrease the deposits of ectopic endometrium. The observation that hyper androgenic states
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| D8399-100MG | 04061833589533 |
| D8399-250MG | 04061833033166 |
| D8399-1G | 04061833589540 |
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