D8399
达那唑
≥98%
别名:
17β-羟基-2,4,17α-妊娠双烯-20-炔并[2,3-d]异恶唑, 2,4,17α-妊娠双烯-20-炔并[2,3-d]异恶唑-17-醇
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关于此项目
经验公式(希尔记法):
C22H27NO2
CAS Number:
分子量:
337.46
EC 号:
MDL编号:
UNSPSC代码:
51111800
PubChem化学物质编号:
NACRES:
NA.77
质量水平
方案
≥98%
表单
powder
药品控制
regulated under CDSA - not available from Sigma-Aldrich Canada
SMILES字符串
CC12Cc3cnoc3C=C1CCC4C2CCC5(C)C4CC[C@@]5(O)C#C
InChI
1S/C22H27NO2/c1-4-22(24)10-8-18-16-6-5-15-11-19-14(13-23-25-19)12-20(15,2)17(16)7-9-21(18,22)3/h1,11,13,16-18,24H,5-10,12H2,2-3H3/t16?,17?,18?,20?,21?,22-/m0/s1
InChI key
POZRVZJJTULAOH-ZIKCMSSPSA-N
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相关类别
生化/生理作用
达那唑是一种弱的雄性激素;垂体前叶抑制剂。
特点和优势
该化合物是由 Sanofi Aventis开发。如需浏览其他药物开发的化合物和批准的药物/候选药物清单,请单击此处。
包装
无底玻璃瓶。内含物装在锥底内插管中。
警示用语:
Warning
危险声明
危险分类
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Repr. 2
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
个人防护装备
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
兴奋剂蛋白同化制剂
H Farkas et al.
Allergy, 67(12), 1586-1593 (2012-10-03)
Hereditary angioedema is a potentially life-threatening disorder, because edema occurring in the mucosa of the upper airways can lead to suffocation. The management of HAE consists of avoiding the triggering factors, prophylaxis, and the acute treatment of edematous episodes. Medical
Timothy J Craig
Allergy and asthma proceedings, 29(3), 225-231 (2008-04-05)
Hereditary angioedema (HAE) is an autosomal dominant disease characterized by painful, recurrent attacks of inflammation affecting the hands, feet, face, abdomen, urogenital tract, and the larynx. The inflammation can be disfiguring, debilitating, quite painful, and, in the case of laryngeal
Pagalavan Letchumanan et al.
Seminars in arthritis and rheumatism, 40(4), 298-306 (2010-06-15)
To review and summarize published information on the use, effectiveness, and adverse effects of danazol in patients with systemic lupus erythematosus (SLE). A MEDLINE search from January 1950 to July 2009 was conducted using 2 search strategies retrieving 51 and
V Selak et al.
The Cochrane database of systematic reviews, (4)(4), CD000068-CD000068 (2007-10-19)
Endometriosis is defined as the presence of endometrial tissue (stromal and glandular) outside the normal uterine cavity. Conventional medical and surgical treatments for endometriosis aim to remove or decrease the deposits of ectopic endometrium. The observation that hyper androgenic states
Terry Gernsheimer et al.
Blood, 121(1), 38-47 (2012-11-15)
A mild thrombocytopenia is relatively frequent during pregnancy and has generally no consequences for either the mother or the fetus. Although representing no threat in the majority of patients, thrombocytopenia may result from a range of pathologic conditions requiring closer
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