D8399
达那唑
≥98%
别名:
17β-羟基-2,4,17α-妊娠双烯-20-炔并[2,3-d]异恶唑, 2,4,17α-妊娠双烯-20-炔并[2,3-d]异恶唑-17-醇
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关于此项目
经验公式（希尔记法）:
C22H27NO2
化学文摘社编号:
分子量:
337.46
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
EC Number:
241-270-1
MDL number:
产品名称
达那唑, ≥98%
InChI key
POZRVZJJTULAOH-ZIKCMSSPSA-N
InChI
1S/C22H27NO2/c1-4-22(24)10-8-18-16-6-5-15-11-19-14(13-23-25-19)12-20(15,2)17(16)7-9-21(18,22)3/h1,11,13,16-18,24H,5-10,12H2,2-3H3/t16?,17?,18?,20?,21?,22-/m0/s1
SMILES string
CC12Cc3cnoc3C=C1CCC4C2CCC5(C)C4CC[C@@]5(O)C#C
assay
≥98%
form
powder
drug control
regulated under CDSA - not available from Sigma-Aldrich Canada
Quality Level
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相关类别
Biochem/physiol Actions
达那唑是一种弱的雄性激素；垂体前叶抑制剂。
Features and Benefits
该化合物是由 Sanofi Aventis开发。如需浏览其他药物开发的化合物和批准的药物/候选药物清单，请单击此处。
Packaging
无底玻璃瓶。内含物装在锥底内插管中。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
兴奋剂蛋白同化制剂
此项目有
Terry Gernsheimer et al.
Blood, 121(1), 38-47 (2012-11-15)
A mild thrombocytopenia is relatively frequent during pregnancy and has generally no consequences for either the mother or the fetus. Although representing no threat in the majority of patients, thrombocytopenia may result from a range of pathologic conditions requiring closer
Hywel D Williams et al.
Journal of pharmaceutical sciences, 101(9), 3360-3380 (2012-05-31)
The Lipid Formulation Classification System Consortium is an industry-academia collaboration, established to develop standardized in vitro methods for the assessment of lipid-based formulations (LBFs). In this first publication, baseline conditions for the conduct of digestion tests are suggested and a
V Selak et al.
The Cochrane database of systematic reviews, (4)(4), CD000068-CD000068 (2007-10-19)
Endometriosis is defined as the presence of endometrial tissue (stromal and glandular) outside the normal uterine cavity. Conventional medical and surgical treatments for endometriosis aim to remove or decrease the deposits of ectopic endometrium. The observation that hyper androgenic states
E Hughes et al.
The Cochrane database of systematic reviews, (1)(1), CD000069-CD000069 (2007-01-27)
The synthetic androgen Danazol, was developed in the 1970's as a treatment for endometriosis. Its use was soon advocated in women with unexplained subfertility. Two randomised trials were subsequently conducted to assess the effectiveness of danazol in this population. The
Johannes Parmentier et al.
International journal of pharmaceutics, 437(1-2), 253-263 (2012-09-04)
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