D8399
达那唑
≥98%
别名:
17β-羟基-2,4,17α-妊娠双烯-20-炔并[2,3-d]异恶唑, 2,4,17α-妊娠双烯-20-炔并[2,3-d]异恶唑-17-醇
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关于此项目
经验公式（希尔记法）:
C22H27NO2
化学文摘社编号:
分子量:
337.46
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
51111800
EC Number:
241-270-1
MDL number:
InChI key
POZRVZJJTULAOH-ZIKCMSSPSA-N
InChI
1S/C22H27NO2/c1-4-22(24)10-8-18-16-6-5-15-11-19-14(13-23-25-19)12-20(15,2)17(16)7-9-21(18,22)3/h1,11,13,16-18,24H,5-10,12H2,2-3H3/t16?,17?,18?,20?,21?,22-/m0/s1
SMILES string
CC12Cc3cnoc3C=C1CCC4C2CCC5(C)C4CC[C@@]5(O)C#C
assay
≥98%
form
powder
drug control
regulated under CDSA - not available from Sigma-Aldrich Canada
Quality Level
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相关类别
Biochem/physiol Actions
达那唑是一种弱的雄性激素；垂体前叶抑制剂。
Features and Benefits
该化合物是由 Sanofi Aventis开发。如需浏览其他药物开发的化合物和批准的药物/候选药物清单，请单击此处。
Packaging
无底玻璃瓶。内含物装在锥底内插管中。
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Repr. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
法规信息
兴奋剂蛋白同化制剂
此项目有
Timothy J Craig
Allergy and asthma proceedings, 29(3), 225-231 (2008-04-05)
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Pagalavan Letchumanan et al.
Seminars in arthritis and rheumatism, 40(4), 298-306 (2010-06-15)
To review and summarize published information on the use, effectiveness, and adverse effects of danazol in patients with systemic lupus erythematosus (SLE). A MEDLINE search from January 1950 to July 2009 was conducted using 2 search strategies retrieving 51 and
H Farkas et al.
Allergy, 67(12), 1586-1593 (2012-10-03)
Hereditary angioedema is a potentially life-threatening disorder, because edema occurring in the mucosa of the upper airways can lead to suffocation. The management of HAE consists of avoiding the triggering factors, prophylaxis, and the acute treatment of edematous episodes. Medical
E Miller
Seminars in veterinary medicine and surgery (small animal), 12(3), 167-169 (1997-08-01)
Currently available therapeutic protocols for immune-mediated diseases in dogs and cats can be associated with poor response rates and a high incidence of side effects. The development of multidrug protocols often results in a synergistic effect that more efficiently suppresses
H Beaumont et al.
The Cochrane database of systematic reviews, (3)(3), CD001017-CD001017 (2007-07-20)
Heavy menstrual bleeding (HMB) is an important cause of ill health in pre menopausal women. Medical therapy, with the avoidance of possibly unnecessary surgery is an attractive treatment option, but there is considerable variation in practice and uncertainty about the
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