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Merck
CN

D8886

Anti-Dehydroepiandrosterone (DHEA) antibody produced in rabbit

whole antiserum, lyophilized powder

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UNSPSC Code:
12352203
NACRES:
NA.41
MDL number:
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biological source

rabbit

conjugate

unconjugated

antibody form

whole antiserum

antibody product type

primary antibodies

clone

polyclonal

form

lyophilized powder

technique(s)

radioimmunoassay: suitable

storage temp.

2-8°C

Immunogen

DHEA-15α-CH2-CO-BSA.

Biochem/physiol Actions

Dehydroepiandrosterone is a sulfated neurosteroid, abundantly present in the brain. It is a strong allosteric modulator of GABAA receptors and has antiseizure and anesthetic properties.

Preparation Note

Reconstitute with 11 ml 0.1 M phosphate buffered saline, pH 7.4, containing 0.1 M gelatin and 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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存储类别

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Mauro Giovanni Carta et al.
Behavioral and brain functions : BBF, 8, 61-61 (2012-12-21)
Neurosteroids are synthesized in the brain and modulate brain excitability. There is increasing evidence of their sedative, anesthetic and antiseizure properties, as well as their influence on mood. Currently neurosteroids are classified as pregnane neurosteroids (allopregnanolone and allotetrahydrodeoxycorticosterone), androstane neurosteroids
Melinda K Shelby et al.
Journal of analytical toxicology, 35(9), 638-655 (2011-11-15)
Because of their perceived and reported effects on self-image, muscle development, performance, and similar factors, anabolic-androgenic steroids (AAS) and their precursors are among the most abused substances by professional, amateur, and recreational athletes. However, AAS abuse is not limited to