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Merck
CN

D8907

1,2-Dioctanoylethylene glycol

~99%

别名:

Ethylene glycol dioctanoate

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关于此项目

经验公式(希尔记法):
C18H34O4
化学文摘社编号:
分子量:
314.46
UNSPSC Code:
41106300
PubChem Substance ID:
MDL number:
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assay

~99%

form

liquid

storage temp.

−20°C

SMILES string

CCCCCCCC(=O)OCCOC(=O)CCCCCCC

InChI

1S/C18H34O4/c1-3-5-7-9-11-13-17(19)21-15-16-22-18(20)14-12-10-8-6-4-2/h3-16H2,1-2H3

InChI key

HTNFLUQQANUSLR-UHFFFAOYSA-N

Biochem/physiol Actions

Potent inhibitor of sn-1,2-diacylglycerol phosphorylation in vitro.


存储类别

12 - Non Combustible Liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

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P Nasmith et al.
Biochemical and biophysical research communications, 161(1), 95-100 (1989-05-30)
The diacylglycerol kinase inhibitors, R59022 and dioctanoylethylene glycol (diC8-eg), potentiate stimulation of the respiratory burst by the chemotactic tripeptide N-formyl-methionyl-leucyl-phenylalanine (fMLP) in human neutrophils. However, in contrast to the potentiation observed in intact cells, neither R59022 nor diC8-eg enhanced the
M Tóth et al.
Acta physiologica Hungarica, 81(4), 341-354 (1993-01-01)
Diacylglycerols (DAG) are assumed to play intracellular signal roles in rapidly growing tissues like those present in the primordial human placenta. The aim of the present study was to gain information on the capacity of DAG-kinase and CDP-choline: DAG phosphocholine
S Bourgoin et al.
The Journal of biological chemistry, 267(17), 11908-11916 (1992-06-15)
To determine the role of protein tyrosine phosphorylation in the activation of phospholipase D (PLD), electropermeabilized HL-60 cells labeled in [3H]alkyl-phosphatidylcholine were treated with vanadate derivatives. Micromolar concentrations of vanadyl hydroperoxide (V(4+)-OOH) induced accumulation of tyrosine-phosphorylated proteins. Concomitantly, V(4+)-OOH or