D9069
N-Desmethyltamoxifen HCl
≥98% (HPLC), solid
别名:
(Z)-2-(p-(1,2-Diphenyl-1-butenyl)phenoxy)-N-methylethylamine, ICI 55,548
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关于此项目
经验公式（希尔记法）:
C25H27NO·HCl
化学文摘社编号:
分子量:
393.95
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352203
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
desiccated
sterility
non-sterile
Quality Segment
assay
≥98% (HPLC)
form
solid
storage condition
desiccated
technique(s)
inhibition assay: suitable
solubility
DMSO: ≥20 mg/mL
shipped in
ambient
storage temp.
room temp
SMILES string
Cl.CC\C(c1ccccc1)=C(/c2ccccc2)c3ccc(OCCNC)cc3
InChI
1S/C25H27NO.ClH/c1-3-24(20-10-6-4-7-11-20)25(21-12-8-5-9-13-21)22-14-16-23(17-15-22)27-19-18-26-2;/h4-17,26H,3,18-19H2,1-2H3;1H/b25-24-;
InChI key
GMLHJWZEYLTNJW-BJFQDICYSA-N
Application
N-Desmethyltamoxifen HCl has been used as an internal standard in high-performance liquid chromatography (HPLC) for the quantification of metabolites from NG2 cell-derived astrocytes.
Biochem/physiol Actions
N-Desmethyltamoxifen HCl is the primary metabolite of tamoxifen. N-Desmethyltamoxifen HCl is an estrogen response modifer and protein kinase C inhibitor.
Features and Benefits
This compound is featured on the Nuclear Receptors (Steroids) and PKC pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
警示词
Danger
危险代码
Hazard Classifications
Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 1B - Repr. 1B
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
怎么回事？
WGK 3
闪点 (F)
Not applicable
闪点 (°C)
Not applicable
PPE（个人防护设备）
dust mask type N95 (US), Eyeshields, Gloves, type P2 (EN 143) respirator cartridges