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D9286

乙基对硫磷

Name: 乙基对硫磷
Brand: SIGMA

≥90%, oil

别名:

O,O-二乙基磷酸对硝基苯酯, 对氧磷, 对硝基苯磷酸二乙酯

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关于此项目

线性分子式:

O₂NC₆H₄OP(O)(OC₂H₅)₂

化学文摘社编号:

311-45-5

分子量:

275.20

UNSPSC Code:

12352202

NACRES:

NA.77

PubChem Substance ID:

24894279

EC Number:

206-221-0

Beilstein/REAXYS Number:

1915526

MDL number:

MFCD00007316

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Quality Level

100

assay

≥90%

form

oil

color

yellow

refractive index

n20/D 1.51 (lit.)

density

1.274 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

CCOP(=O)(OCC)Oc1ccc(cc1)[N+]([O-])=O

InChI

1S/C10H14NO6P/c1-3-15-18(14,16-4-2)17-10-7-5-9(6-8-10)11(12)13/h5-8H,3-4H2,1-2H3

InChI key

WYMSBXTXOHUIGT-UHFFFAOYSA-N

Gene Information

human ... PON1(5444)

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Application

乙基对氧磷被用作对氧磷酶（PON）活性测定的底物。它还被用作脂肪酶抑制剂，以研究安塞曲匹对体内高密度脂蛋白L3（HDL3）向HDL2的同型转移的影响。

Biochem/physiol Actions

强效不可逆乙酰胆碱酯酶抑制剂

Physical form

油性液体

Disclaimer

对空气敏感：在氩气下处理

pictograms

GHS06,GHS09

signalword

Danger

hcodes

H300 + H310,H410

pcodes

P262 - P264 - P273 - P280 - P301 + P310 - P302 + P352 + P310

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Oral - Aquatic Acute 1 - Aquatic Chronic 1

存储类别

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

法规信息

危险化学品

剧毒化学品

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Obesity-Associated Metabolic Disturbances Reverse the Antioxidant and Anti-Inflammatory Properties of High-Density Lipoproteins in Microglial Cells.

Elena Grao-Cruces et al.

Biomedicines, 9(11) (2021-11-28)

High-density lipoproteins (HDLs) play an important role in reverse cholesterol transport and present antioxidant properties, among others. In the central nervous system (CNS), there are HDLs, where these lipoproteins could influence brain health. Owing to the new evidence of HDL

Inhibition of cholesteryl ester transfer protein increases cholesteryl ester content of large HDL independently of HDL-to-HDL homotypic transfer: in vitro vs in vivo comparison using anacetrapib and dalcetrapib

Johns DG, et al.

European Journal of Pharmacology, 762, 256-262 (2015)

Exercise intervention alters HDL subclass distribution and function in obese women

Woudberg NJ, et al.

Lipids in Health and Disease, 17(1), 232-232 (2018)

Exercise intervention alters HDL subclass distribution and function in obese women.

Nicholas J Woudberg et al.

Lipids in health and disease, 17(1), 232-232 (2018-10-12)

Obesity is associated with a change in high-density lipoprotein (HDL) function and subclass. Exercise training reduces cardiovascular risk in obese patients. We aimed to explore the effect of an exercise training stimulus on HDL functionality and subclass in obese women.

Altered lipoproteins in patients with systemic lupus erythematosus are associated with augmented oxidative stress: a potential role in atherosclerosis

Park JK, et al.

Arthritis Research & Therapy, 18(1), 306-306 (2016)

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全球贸易项目编号

货号	GTIN
D9286-1G	04061833590584

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