This article provides an update about catecholamine metabolism, with emphasis on correcting common misconceptions relevant to catecholamine systems in health and disease. Importantly, most metabolism of catecholamines takes place within the same cells where the amines are synthesized. This mainly

Cerebrospinal fluid biomarkers of central catecholamine deficiency in Parkinson's disease and other synucleinopathies.

David S Goldstein et al.

Brain : a journal of neurology, 135(Pt 6), 1900-1913 (2012-03-28)

Central catecholamine deficiency characterizes α-synucleinopathies such as Parkinson's disease. We hypothesized that cerebrospinal fluid levels of neuronal metabolites of catecholamines provide neurochemical biomarkers of these disorders. To test this hypothesis we measured cerebrospinal fluid levels of catechols including dopamine, norepinephrine

Deficits in ventromedial prefrontal cortex group 1 metabotropic glutamate receptor function mediate resistance to extinction during protracted withdrawal from an extensive history of cocaine self-administration.

Osnat Ben-Shahar et al.

The Journal of neuroscience : the official journal of the Society for Neuroscience, 33(2), 495-506a-495-506a (2013-01-11)

Anomalies in prefrontal cortex (PFC) function are posited to underpin difficulties in learning to suppress drug-seeking behavior during abstinence. Because group 1 metabotropic glutamate receptors (mGluRs) regulate drug-related learning, we assayed the consequences of extended access to intravenous cocaine (6

Postsynaptic mGluR mediated excitation of neurons in midbrain periaqueductal grey.

Adrianne R Wilson-Poe et al.

Neuropharmacology, 66, 348-354 (2012-07-10)

Metabotropic glutamate (mGlu) receptors modulate pain from within the midbrain periaqueductal grey (PAG). In the present study, the postsynaptic mGlu receptor mediated effects on rat PAG neurons were examined using whole-cell patch-clamp recordings in brain slices. The selective group I

Tet1 is critical for neuronal activity-regulated gene expression and memory extinction.

Andrii Rudenko et al.

Neuron, 79(6), 1109-1122 (2013-09-21)

The ten-eleven translocation (Tet) family of methylcytosine dioxygenases catalyze oxidation of 5-methylcytosine (5mC) to 5-hydroxymethylcytosine (5hmC) and promote DNA demethylation. Despite the abundance of 5hmC and Tet proteins in the brain, little is known about the functions of the neuronal

查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持

DL-3,4-二羟基苯基二醇

关于此项目

主要文件

属性

表单

质量水平

储存温度

SMILES字符串

InChI

InChI key

安全信息

象形图

警示用语：

危险声明

预防措施声明

危险分类

储存分类代码

WGK

个人防护装备

文件

分析证书(COA)

已有该产品？

同行评审论文

技术服务