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E0251

Estrone 3-sulfate sodium salt

Name: Estrone 3-sulfate sodium salt
Brand: SIGMA

synthetic (organic), ≥98% (TLC), Inactive estrogen, powder

别名:

1,3,5(10)-Estratrien-17-one 3-sulfate

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关于此项目

线性分子式:

C₁₈H₂₁O₅SNa

化学文摘社编号:

438-67-5

分子量:

372.41

UNSPSC Code:

12352202

PubChem Substance ID:

24894364

NACRES:

NA.77

MDL number:

MFCD00070035

Assay:

≥98% (TLC)

Form:

powder

Quality level:

200

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产品名称

Estrone 3-sulfate sodium salt, contains ~35% Tris as stabilizer

biological source

synthetic (organic)

Quality Level

200

sterility

non-sterile

assay

≥98% (TLC)

form

powder

contains

~35% Tris as stabilizer

technique(s)

inhibition assay: suitable

solubility

methanol: 19.60-20.40 mg/mL, clear, colorless to faintly yellow

shipped in

ambient

storage temp.

−20°C

SMILES string

[Na].[H][C@]12CC[C@]3(C)C(=O)CC[C@@]3([H])[C@]1([H])CCc4cc(OS(O)(=O)=O)ccc24

InChI

1S/C18H22O5S.Na.H/c1-18-9-8-14-13-5-3-12(23-24(20,21)22)10-11(13)2-4-15(14)16(18)6-7-17(18)19;;/h3,5,10,14-16H,2,4,6-9H2,1H3,(H,20,21,22);;/t14-,15-,16+,18+;;/m1../s1

InChI key

GQZNDBBLTDOIBE-DLEHHZMWSA-N

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Packaging

Package size based on steroid content

pictograms

GHS08

signalword

Danger

hcodes

H351,H360,H362

pcodes

P202 - P260 - P263 - P264 - P270 - P308 + P313

Hazard Classifications

Carc. 2 - Lact. - Repr. 1A

存储类别

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

涉药品监管产品

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

0000508192

0000519056

0000481181

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Suppression of cell proliferation by inhibition of estrone-3-sulfate transporter in estrogen-dependent breast cancer cells.

Takashi Nozawa et al.

Pharmaceutical research, 22(10), 1634-1641 (2005-09-24)

The aim of the study is to suppress the progress of estrogen-dependent breast cancer by inhibiting the membrane transporter, which mediates the internalization of estrone-3-sulfate as estrogen precursor in the cancer cells. The uptake of estrone-3-sulfate by estrogen-dependent breast cancer

Estrogen and androgen receptor expression in relation to steroid concentrations in the adult boar epididymis.

Christopher A Pearl et al.

Domestic animal endocrinology, 33(4), 451-459 (2006-10-13)

The steroid hormone regulation of the epididymis in a high estrogen producing animal like the boar is not currently understood. To test the hypothesis that the boar epididymis is an estrogen and androgen responsive tissue, the presence of estrogen and

Comparison of different regimens of estradiol benzoate treatments followed by long-acting progesterone to prepare noncycling mares as embryo recipients.

E S M Silva et al.

Theriogenology, 86(7), 1749-1756 (2016-08-09)

The present study evaluated the influence of different regimens of estradiol benzoate (EB) treatments followed by a single dose of long-acting progesterone (LA P4) on plasma estrogen and P4 concentrations in noncyclic mares prepared as embryo recipients. Twenty-one anestrous mares

Vascular endothelial growth factor A (VEGFA) modulates bovine placenta steroidogenesis in vitro.

L M M C Sousa et al.

Placenta, 33(10), 788-794 (2012-07-31)

Our objectives were to investigate the possible role of VEGFA in bovine placenta steroid synthesis and to determine whether cloned derived placental cells present similar responses as non-cloned ones. Placental cells from cloned (term) and non-cloned (days 90, 150, 210

Differential role of organic anion-transporting polypeptides in estrone-3-sulphate uptake by breast epithelial cells and breast cancer cells.

Nilasha Banerjee et al.

The Journal of pharmacology and experimental therapeutics, 342(2), 510-519 (2012-05-17)

The purpose of this study was to investigate the differential expression and function of organic anion-transporting polypeptides (OATPs) in breast epithelial and breast cancer cells. Estrone-3-sulfate (E3S), a substrate for 7 of 11 OATPs, is a predominant source of tumor

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全球贸易项目编号

货号	GTIN
E0251-100MG	04061833600986
E0251-1G	04061826236451

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