产品名称
Erythropoietin Soluble Receptor human, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder
biological source
human
recombinant
expressed in NSO cells
assay
>90% (SDS-PAGE)
form
lyophilized powder
potency
74 ng/mL
mol wt
~25 kDa
packaging
pkg of 50 μg
storage condition
avoid repeated freeze/thaw cycles
impurities
endotoxin, tested
UniProt accession no.
storage temp.
−20°C
Quality Level
Gene Information
human ... EPOR(2057)
Analysis Note
The biological activity is measured by its ability to inhibit the recombinant human erythropoietin mediated cell proliferation of human TF1 cells.
Biochem/physiol Actions
Binds erthropoietin with high affinity and is an erythropoietin antagonist.
Recombinant human soluble erythropoietin receptor binds erthropoietin with high affinity and is an erythropoietin antagonist.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing 5% trehalose and 50 ug of bovine serum albumin per 1 ug of cytokine.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
含少量动物源组分生物产品
常规特殊物品
此项目有
Soluble Erythropoietin Receptor Contributes To Erythropoietin Resistance In End-stage Renal Disease.
Khankin, E.V., et al.
PLoS Biology, 5, e9246-e9246 (2010)
T Kitamura et al.
Journal of cellular physiology, 140(2), 323-334 (1989-08-01)
We have established a novel cell line, designated as TF-1, from a patient with erythroleukemia, which showed complete growth dependency on granulocyte-macrophage colony-stimulating factor (GM-CSF) or on interleukin-3 (IL-3) and carried a homogeneous chromosomal abnormality (54X). Erythropoietin (EPO) also sustained
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